Three-time defending champion Roger Federer was seeded number one at the US Open for the fourth consecutive year, and Justine Henin topped the women’s seedings.

Thirteen players who have won Grand Slam titles are among the 32 men and 32 women seeded for the last major tournament of the year.

That includes men’s number two Rafael Nadal, the three-time French Open champion, and number five Andy Roddick, who won the 2003 US Open and lost to Federer in last year’s final.

Novak Djokovic is seeded third, Nikolay Davydenko -- involved in a match that sparked an ATP betting probe this month -- is the fourth seed and James Blake is seeded sixth.

Defending champion Maria Sharapova is seeded number two in the women’s field, followed by number three Jelena Jankovic, number four Svetlana Kuznetsova and number five Ana Ivanovic.

Sharapova and Kuznetsova are two of the seven Russian women who were seeded, joined by number six Anna Chakvetadze, seventh seed Nadia Petrova, number 14 Elena Dementieva, number 15 Dinara Safina and number 27 Vera Zvonareva.

Sisters Serena and Venus Williams, who have each won the US Open twice, were the only American women seeded, with Serena at number eight and Venus at number 12. Roddick and Blake were the only American men in the seedings.

Federer, bidding for his 12th Grand Slam title, will try to become the first man since the 1920s to win the US championship four years in a row.

Henin won the US Open in 2003 and was the runner-up to Sharapova last year.

The US Open followed the ATP and WTA rankings to determine seedings.

The draw for the tournament is on Wednesday, and play begins next Monday.