Press Esc to close
Monday 27 February 2017
News updated at 1:52 AM IST
Weather
Max: 35.5°C
Min : 19.7°C
In Bengaluru
clear sky

Sperms from the same man have big genetic differences: study

London, Jul 20, 2012, PTI:
For the first time, scientists have obtained genetic blueprints of almost 100 sperms from a single individual to confirm that they differ hugely from each other.

And this difference goes on to determine which sperm will finally make it to the female egg.

In the study, scientists scanned 100 sperms from one man. They found that every sperm was different because of the way their inherited DNA is shuffled, the 'Daily Mail' reported.

The process, known as recombination, mixes up genes passed down by a man's mother and father and increases genetic diversity.

Each of the sperms studied showed an average of 23 recombination (mixing) events. But individual sperm varied greatly in the way they experienced spontaneous genetic mutations.

The study found every sperm containing between 25 and 36 'new' mutations, not seen in other body cells. Two sperms were found to be missing entire chromosomes, the protein-bound packages of DNA that contain the genes.

Random mutations create genetic variation, but can be harmful if they occur in the wrong places.

The cells were donated by a 40-year-old man who has healthy offspring and normally functioning sperms.

"For the first time we were able to generate an individual recombination map and mutation rate for each of several sperm from one person," said Professor Barry Behr, from Stanford University in California, US.

"Now we can look at a particular individual, make some calls about what they would likely contribute genetically to an embryo, and perhaps even diagnose or detect potential problems," said Behr.

Genetically sequencing sperm could provide a "new kind of early detection system" to identify men who may have trouble conceiving, he added.
The research is published in the journal Cell.

Most cells in the human body have two copies each of 23 chromosomes, containing DNA inherited from both parents. However, sperm in men and eggs in women only have single copies.

 

Go to Top

Photo Gallery
Art lovers ging through the paintings exhibited at Taj Gateway organised by Round Table India...

Art lovers ging through the paintings exhibited at Taj Gateway organised by Round Table India...

Bhojpuri actor Ravi Kishan, who recently joined BJP, addresses an election rally in Mirzapur...

Bhojpuri actor Ravi Kishan, who recently joined BJP, addresses an election rally in Mirzapur...

Union Textiles Minister and BJP leader Smriti Zubin Irani (speaking from the podium) poses...

Union Textiles Minister and BJP leader Smriti Zubin Irani (speaking from the podium) poses...

AAP workers smash a hoarding as they protest outside the party office over alleged discrepencies...

AAP workers smash a hoarding as they protest outside the party office over alleged discrepencies...

Bollywood actress Sonal Chauhan walks the ramp during the Jaipur Couture Fashion Show...

Bollywood actress Sonal Chauhan walks the ramp during the Jaipur Couture Fashion Show...

Cricket icon Sachin Tendulkar gestures while flaging off IDBI Federal Life Insurance's New...

Cricket icon Sachin Tendulkar gestures while flaging off IDBI Federal Life Insurance's New...

A pair of parrots collecting nectar from Palash flower at a garden in New Delhi ...

A pair of parrots collecting nectar from Palash flower at a garden in New Delhi ...

Police inspect after a gas tanker collided with a tree at National Highway near Bihuguri of Tezpur..

Police inspect after a gas tanker collided with a tree at National Highway near Bihuguri of Tezpur..

Bikers perform stunts at an event in Faridabad...

Bikers perform stunts at an event in Faridabad...

Tracks laid out for the NEXA P1 Powerboat, Indian Grand Prix of the Seas, the global series...

Tracks laid out for the NEXA P1 Powerboat, Indian Grand Prix of the Seas, the global series...

Like us on Facebook

Copyright 2017, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523