Press Esc to close
Saturday 28 May 2016
News updated at 2:57 AM IST
Weather
Max: 33.2°C
Min : 22.2°C
In Bengaluru
Partially cloudy

Sperms from the same man have big genetic differences: study

London, Jul 20, 2012, PTI:

For the first time, scientists have obtained genetic blueprints of almost 100 sperms from a single individual to confirm that they differ hugely from each other.

And this difference goes on to determine which sperm will finally make it to the female egg.

In the study, scientists scanned 100 sperms from one man. They found that every sperm was different because of the way their inherited DNA is shuffled, the 'Daily Mail' reported.

The process, known as recombination, mixes up genes passed down by a man's mother and father and increases genetic diversity.

Each of the sperms studied showed an average of 23 recombination (mixing) events. But individual sperm varied greatly in the way they experienced spontaneous genetic mutations.

The study found every sperm containing between 25 and 36 'new' mutations, not seen in other body cells. Two sperms were found to be missing entire chromosomes, the protein-bound packages of DNA that contain the genes.

Random mutations create genetic variation, but can be harmful if they occur in the wrong places.

The cells were donated by a 40-year-old man who has healthy offspring and normally functioning sperms.

"For the first time we were able to generate an individual recombination map and mutation rate for each of several sperm from one person," said Professor Barry Behr, from Stanford University in California, US.

"Now we can look at a particular individual, make some calls about what they would likely contribute genetically to an embryo, and perhaps even diagnose or detect potential problems," said Behr.

Genetically sequencing sperm could provide a "new kind of early detection system" to identify men who may have trouble conceiving, he added.
The research is published in the journal Cell.

Most cells in the human body have two copies each of 23 chromosomes, containing DNA inherited from both parents. However, sperm in men and eggs in women only have single copies.


Go to Top

Photo Gallery
An elephant herd seen near a village of Mysore city...

An elephant herd seen near a village of Mysore city...

Y Jyothi (R) of Telangana competes to win gold in the 100m girls hurdles...

Y Jyothi (R) of Telangana competes to win gold in the 100m girls hurdles...

Carpenters completing the construction of the wheels for the forthcoming Lord Jagannath Yatra...

Carpenters completing the construction of the wheels for the forthcoming Lord Jagannath Yatra...

Obama stands after laying a wreath at the Hiroshima Peace Memorial Park in Hiroshima...

Obama stands after laying a wreath at the Hiroshima Peace Memorial Park in Hiroshima...

Army personnel take positions during an encounter with the militants at Naugam...

Army personnel take positions during an encounter with the militants at Naugam...

Aishwarya Rai Bachchan during the event organised to celebrate the success of film Sarbjit ...

Aishwarya Rai Bachchan during the event organised to celebrate the success of film Sarbjit ...

Girl takes selfie with Prime Minister Narendra Modi at exhibition on achievements of North East...

Girl takes selfie with Prime Minister Narendra Modi at exhibition on achievements of North East...

Army Jawans leaving after the encounter at Khonchipora village in Tangmarg...

Army Jawans leaving after the encounter at Khonchipora village in Tangmarg...

Bihar Police persons pays tributes  Jawaharlal Nehru on his 52nd death anniversary...

Bihar Police persons pays tributes Jawaharlal Nehru on his 52nd death anniversary...

Akshay Kumar, Jacqueline,  Liza Headen and Abhishek at a promotional event of 'Housefull 3'...

Akshay Kumar, Jacqueline, Liza Headen and Abhishek at a promotional event of 'Housefull 3'...

Copyright 2014, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523