Press Esc to close
Tuesday 02 September 2014
News updated at 5:00 PM IST
Weather
Max: 27°C
Min : 20°C
In Bangalore
Generally cloudy

Sperms from the same man have big genetic differences: study

London, Jul 20, 2012, PTI:

For the first time, scientists have obtained genetic blueprints of almost 100 sperms from a single individual to confirm that they differ hugely from each other.

And this difference goes on to determine which sperm will finally make it to the female egg.

In the study, scientists scanned 100 sperms from one man. They found that every sperm was different because of the way their inherited DNA is shuffled, the 'Daily Mail' reported.


The process, known as recombination, mixes up genes passed down by a man's mother and father and increases genetic diversity.

Each of the sperms studied showed an average of 23 recombination (mixing) events. But individual sperm varied greatly in the way they experienced spontaneous genetic mutations.

The study found every sperm containing between 25 and 36 'new' mutations, not seen in other body cells. Two sperms were found to be missing entire chromosomes, the protein-bound packages of DNA that contain the genes.

Random mutations create genetic variation, but can be harmful if they occur in the wrong places.

The cells were donated by a 40-year-old man who has healthy offspring and normally functioning sperms.

"For the first time we were able to generate an individual recombination map and mutation rate for each of several sperm from one person," said Professor Barry Behr, from Stanford University in California, US.

"Now we can look at a particular individual, make some calls about what they would likely contribute genetically to an embryo, and perhaps even diagnose or detect potential problems," said Behr.

Genetically sequencing sperm could provide a "new kind of early detection system" to identify men who may have trouble conceiving, he added.
The research is published in the journal Cell.

Most cells in the human body have two copies each of 23 chromosomes, containing DNA inherited from both parents. However, sperm in men and eggs in women only have single copies.

Go to Top

Photo Gallery
President Pranab Mukherjee grants degree to a student at the 14th convocation of the University...

President Pranab Mukherjee grants degree to a student at the 14th convocation of the University...

Fireworks on the occasion of 410th installation anniversary of Sri Guru Granth Sahib, the holy...

Fireworks on the occasion of 410th installation anniversary of Sri Guru Granth Sahib, the holy...

Left Front activists take part in a rally to observe anti-imperialist day in Kolkata on...

Left Front activists take part in a rally to observe anti-imperialist day in Kolkata on...

Flood water flows through Srisailam dam after its four crest gates were opened in Kurnool on...

Flood water flows through Srisailam dam after its four crest gates were opened in Kurnool on...

BJP president Amit Shah during a visit to Sree Padmanabhaswamy temple in Thiruvananthapuram on...

BJP president Amit Shah during a visit to Sree Padmanabhaswamy temple in Thiruvananthapuram on...

Prime Minister Narendra Modi shakes hands with Japanese Minister of Foreign Affairs Fumio...

Prime Minister Narendra Modi shakes hands with Japanese Minister of Foreign Affairs Fumio...

Actress & BJP MP from Chandigarh Kirron Kher speaks during a seminar on...

Actress & BJP MP from Chandigarh Kirron Kher speaks during a seminar on...

Prime Minister Narendra Modi and Japan's Prime Minister Shinzo Abe makes a toast during a banquet...

Prime Minister Narendra Modi and Japan's Prime Minister Shinzo Abe makes a toast during a banquet...

Congress president Sonia Gandhi prays in a temple during a visit to her constituency Rae Bareli...

Congress president Sonia Gandhi prays in a temple during a visit to her constituency Rae Bareli...

Congress president Sonia Gandhi in a village hut during a visit to her constituency Rae Bareli on...

Congress president Sonia Gandhi in a village hut during a visit to her constituency Rae Bareli on...

Copyright 2014, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bangalore - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523