Press Esc to close

Sperms from the same man have big genetic differences: study

London, Jul 20, 2012, PTI: 14:17 IST
For the first time, scientists have obtained genetic blueprints of almost 100 sperms from a single individual to confirm that they differ hugely from each other.

And this difference goes on to determine which sperm will finally make it to the female egg.

In the study, scientists scanned 100 sperms from one man. They found that every sperm was different because of the way their inherited DNA is shuffled, the 'Daily Mail' reported.

The process, known as recombination, mixes up genes passed down by a man's mother and father and increases genetic diversity.

Each of the sperms studied showed an average of 23 recombination (mixing) events. But individual sperm varied greatly in the way they experienced spontaneous genetic mutations.

The study found every sperm containing between 25 and 36 'new' mutations, not seen in other body cells. Two sperms were found to be missing entire chromosomes, the protein-bound packages of DNA that contain the genes.

Random mutations create genetic variation, but can be harmful if they occur in the wrong places.

The cells were donated by a 40-year-old man who has healthy offspring and normally functioning sperms.

"For the first time we were able to generate an individual recombination map and mutation rate for each of several sperm from one person," said Professor Barry Behr, from Stanford University in California, US.

"Now we can look at a particular individual, make some calls about what they would likely contribute genetically to an embryo, and perhaps even diagnose or detect potential problems," said Behr.

Genetically sequencing sperm could provide a "new kind of early detection system" to identify men who may have trouble conceiving, he added.
The research is published in the journal Cell.

Most cells in the human body have two copies each of 23 chromosomes, containing DNA inherited from both parents. However, sperm in men and eggs in women only have single copies.

Go to Top

Photo Gallery
CPI(M) workers chant slogans at a protest rally outside BJP headquarters in New Delhi on Tuesday...

CPI(M) workers chant slogans at a protest rally outside BJP headquarters in New Delhi on Tuesday...

Woman teachers pose with Diwali greeting messages at a school in Moradabad on Tuesday...

Woman teachers pose with Diwali greeting messages at a school in Moradabad on Tuesday...

A girl buying decorative items in a market on the occasion of Dhanteras festival in Bhopal on ...

A girl buying decorative items in a market on the occasion of Dhanteras festival in Bhopal on ...

Vendors show lanterns to customers at a roadside market ahead of the Hindu festival of Diwali in ...

Vendors show lanterns to customers at a roadside market ahead of the Hindu festival of Diwali in ...

BJP National President Amit Shah and BJP Kerala state president Kummanam Rajasekharan wave to the ..

BJP National President Amit Shah and BJP Kerala state president Kummanam Rajasekharan wave to the ..

England Midfielder Callum Hudson-Odoi(14) and Hinata Kida(6),Midfielder of Japan vie for the ball ..

England Midfielder Callum Hudson-Odoi(14) and Hinata Kida(6),Midfielder of Japan vie for the ball ..

Actress and BJP MP Hema Malini along with her daughters Ahana and Esha cutting a cake to celebrate..

Actress and BJP MP Hema Malini along with her daughters Ahana and Esha cutting a cake to celebrate..

Union Minister for Defence, Nirmala Sitharaman with Chief of Naval Staff, Admiral Sunil Lanba and ..

Union Minister for Defence, Nirmala Sitharaman with Chief of Naval Staff, Admiral Sunil Lanba and ..

Kamaraj Congress (KKC) and Most Backward Communities Federation demonstrators lying on the road in..

Kamaraj Congress (KKC) and Most Backward Communities Federation demonstrators lying on the road in..

Rajesh Talwar arrives at his residence in Noida on Monday after he, along with his wife Nupur, was..

Rajesh Talwar arrives at his residence in Noida on Monday after he, along with his wife Nupur, was..

Like us on Facebook

Copyright 2017, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523
Powered by Yodasoft Technologies Pvt. Ltd.