Press Esc to close
Sunday 22 January 2017
News updated at 9:38 PM IST
Weather
Max: 28.9°C
Min : 15.3°C
In Bengaluru
Sunny day

Formula food toxic for premature baby's cells

Washington, Dec 11, 2012, PTI:

Unsafe feed

Infant formula causes cellular death that may contribute to necrotising enterocolitis, a severe intestinal condition that is often fatal and occurs most commonly in premature infants, says a new study.

University of California San Diego bio-engineers, based their study on tests comparing the digestion of fresh human breast milk and nine different infant formulas.

Scientists have long known that premature infants fed formula are more likely to develop necrotizing enterocolitis than those fed breast milk.

The condition is the leading cause of death from gastrointestinal diseases in premature infants, but the underlying mechanism has not been understood, the journal Paediatric Research reported.

Alexander Penn, working in the Microcirculation Lab of Geert Schmid-Schonbein, bio-engineering professor from the UC San Diego Jacobs School of Engineering, believes they have come closer to an answer, according to a California statement.
The intestines of healthy adults and older children have a mature mucosal barrier that may prevent damage due to free fatty acids.

However, the intestine is leakier at birth, particularly for pre-term infants, which could be why they are more susceptible to necrotising enterocolitis.

Therefore, the researchers wanted to know what happens to breast milk as compared to infant formula when they are exposed to digestive enzymes.

Overwhelmingly, the digestion of formula led to cellular death, or cytotoxicity - in less than five minutes in some cases - while breast milk did not.

For example, digestion of formula caused death in 47 percent to 99 percent of neutrophils while only six percent of them died as a result of milk digestion.

The study found that breast milk appears to have a built-in mechanism to prevent cytotoxicity.

The research team believes most food, like formula, releases high levels of free fatty acids during digestion, but that breast milk is digested in a slower, more controlled, process.

Currently, many neonatal intensive care units are moving towards formula-free environments, but breastfeeding a premature infant can be challenging or physically impossible and supplies of donor breast milk are limited.

 

Go to Top

Photo Gallery
Olympic finalist Gymnast Dipa Karmakar being felicitated with Assames japi,Khoria and gomacha...

Olympic finalist Gymnast Dipa Karmakar being felicitated with Assames japi,Khoria and gomacha...

A boat man carries Hindu devotees in the river Yamuna early in the morning during magh Mela in...

A boat man carries Hindu devotees in the river Yamuna early in the morning during magh Mela in...

Austria's Michael Matt speeds down the course during an alpine ski, men's World Cup slalom...

Austria's Michael Matt speeds down the course during an alpine ski, men's World Cup slalom...

Punjab tableaux artists pose a photo during a press preview in New Delhi on Sunday...

Punjab tableaux artists pose a photo during a press preview in New Delhi on Sunday...

AIADMK leader SP Velumani inaugurates Cattle race after the urgent law was passed for...

AIADMK leader SP Velumani inaugurates Cattle race after the urgent law was passed for...

Bollywood actors Madhuri Dixit and Manish Paul atteded the Umang Mumbai Police Show 2017 in...

Bollywood actors Madhuri Dixit and Manish Paul atteded the Umang Mumbai Police Show 2017 in...

Youngstres and Students during the protest to Lift ban on jallikattu and impose ban on PETA...

Youngstres and Students during the protest to Lift ban on jallikattu and impose ban on PETA...

India Captain Virat Kohli celebrate after his 50 runs during 3rd ODI against England at Eden...

India Captain Virat Kohli celebrate after his 50 runs during 3rd ODI against England at Eden...

Rescue and relief work in progress at the site where Jagdalpur-Bhubaneswar Express train derailed...

Rescue and relief work in progress at the site where Jagdalpur-Bhubaneswar Express train derailed...

Samajwadi Party Vice president Kiranmoy Nanda, SP state president Naresh Utam and Congress state...

Samajwadi Party Vice president Kiranmoy Nanda, SP state president Naresh Utam and Congress state...

Like us on Facebook

Copyright 2014, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523