Saturday 19 April 2014
News updated at 1:04 AM IST
Weather
Max: 35.4°C
Min : 22.5°C
In Bangalore
Sunny day

Widely prescribed amoxicillin not only useless, harmful too

London, Dec 20, 2012, PTI:

Commonly prescribed antibiotic - amoxicillin - is ineffective for treating coughs and other chest infections, and can be harmful if overused, experts claim.

The overuse of the antibiotic can lead to side effects such as diarrhoea, rash, vomiting and the development of resistance, researchers warned.

“Patients given amoxicillin don’t recover much quicker or have significantly fewer symptoms,” said researcher Paul Little from the University of Southampton.


“Indeed, using amoxicillin to treat respiratory infections in patients not suspected of having pneumonia is not likely to help and could be harmful,” Little said in a statement.

LRTI (chest infections) are one of the most common acute illnesses treated in primary
care in developed countries.

In the study, 2,061 adults with acute uncomplicated LRTI from primary care practices in 12 European countries - including England, the Netherlands, Belgium, Germany, Sweden, France, Italy, Spain and Poland - were randomly assigned to receive either amoxicillin or a placebo three times a day for seven days.

Little difference in severity or duration of symptoms was reported between the two groups. This was true even for older patients aged 60 or more who were generally healthy, in whom antibiotics appeared to have a very limited effect.

Although significantly more patients in the placebo group experienced new or worsening symptoms (19.3 per cent vs 15.9 per cent), the number needed to treat was high (30), and just two patients in the placebo group and one in the antibiotic group required hospitalisation.

Patients taking antibiotics reported significantly more side effects including nausea, rash, and diarrhea, than those given placebo.

“Our results show that most people get better on their own. But, given that a small number of patients will benefit from antibiotics the challenge remains to identify these individuals.” Little said.

Go to Top

Photo Gallery
Catholic devotees attend a Good Friday Mass inside at a church in New Delhi...

Catholic devotees attend a Good Friday Mass inside at a church in New Delhi...

Fire fighters trying to douse a fire that broke out at a shopping complex in Noida...

Fire fighters trying to douse a fire that broke out at a shopping complex in Noida...

SSB soldiers during the passing out parade of the 6th batch at Sashastra Seema Bal...

SSB soldiers during the passing out parade of the 6th batch at Sashastra Seema Bal...

A girl lights a candle on a graveyard of Central baptist Church's central graveyard...

A girl lights a candle on a graveyard of Central baptist Church's central graveyard...

Christian devotees take part in a 'Good Friday' procession in Jammu...

Christian devotees take part in a 'Good Friday' procession in Jammu...

A potter making earthen pots during summer season in Mirzapur on Friday. PTI Photo

A potter making earthen pots during summer season in Mirzapur on Friday. PTI Photo

Samajwadi Party workers attempt self-immolation with kerosene oil during a protest against ...

Samajwadi Party workers attempt self-immolation with kerosene oil during a protest against ...

Members of People for the Ethical Treatment of Animals (PETA), dressed as bloodied rabbits ...

Members of People for the Ethical Treatment of Animals (PETA), dressed as bloodied rabbits ...

Mutupallaku fesitval procession at Coonoor near Ooty on Friday. PTI Photo

Mutupallaku fesitval procession at Coonoor near Ooty on Friday. PTI Photo

A girl child kissing a statue of Jesus Christ on the occasion of Good Friday at The Sacred Heart...

A girl child kissing a statue of Jesus Christ on the occasion of Good Friday at The Sacred Heart...

Copyright 2014, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bangalore - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523