Press Esc to close

Widely prescribed amoxicillin not only useless, harmful too

London, Dec 20, 2012, PTI: 21:36 IST
Commonly prescribed antibiotic - amoxicillin - is ineffective for treating coughs and other chest infections, and can be harmful if overused, experts claim.

The overuse of the antibiotic can lead to side effects such as diarrhoea, rash, vomiting and the development of resistance, researchers warned.

“Patients given amoxicillin don’t recover much quicker or have significantly fewer symptoms,” said researcher Paul Little from the University of Southampton.

“Indeed, using amoxicillin to treat respiratory infections in patients not suspected of having pneumonia is not likely to help and could be harmful,” Little said in a statement.

LRTI (chest infections) are one of the most common acute illnesses treated in primary
care in developed countries.

In the study, 2,061 adults with acute uncomplicated LRTI from primary care practices in 12 European countries - including England, the Netherlands, Belgium, Germany, Sweden, France, Italy, Spain and Poland - were randomly assigned to receive either amoxicillin or a placebo three times a day for seven days.

Little difference in severity or duration of symptoms was reported between the two groups. This was true even for older patients aged 60 or more who were generally healthy, in whom antibiotics appeared to have a very limited effect.

Although significantly more patients in the placebo group experienced new or worsening symptoms (19.3 per cent vs 15.9 per cent), the number needed to treat was high (30), and just two patients in the placebo group and one in the antibiotic group required hospitalisation.

Patients taking antibiotics reported significantly more side effects including nausea, rash, and diarrhea, than those given placebo.

“Our results show that most people get better on their own. But, given that a small number of patients will benefit from antibiotics the challenge remains to identify these individuals.” Little said.

Go to Top

Photo Gallery
Rashtriya Swayamsevak Sangh (RSS) volunteers taking...

Rashtriya Swayamsevak Sangh (RSS) volunteers taking...

Air Chief Marshal BS Dhanoa, Chief of the Air Staff...

Air Chief Marshal BS Dhanoa, Chief of the Air Staff...

SUCI activists stage a protest rally against State...

SUCI activists stage a protest rally against State...

Mick Jagger of the Rolling Stones performs during the...

Mick Jagger of the Rolling Stones performs during the...

Mime artist Ujjal Kar gets ready to perform as Charlie Chaplin...

Mime artist Ujjal Kar gets ready to perform as Charlie Chaplin...

Acid attack survivor Mohi walks the ramp along with...

Acid attack survivor Mohi walks the ramp along with...

People buying Sugar Canes in a market for upcoming...

People buying Sugar Canes in a market for upcoming...

Britain's Foreign Secretary, Boris Johnson, arrives to speak at the Chatham...

Britain's Foreign Secretary, Boris Johnson, arrives to speak at the Chatham...

Actress Katerina Lehou as high priestess, passes the Olympic Flame onto...

Actress Katerina Lehou as high priestess, passes the Olympic Flame onto...

Tamil Nadu coach L Balaji with R Ashwin at BKC...

Tamil Nadu coach L Balaji with R Ashwin at BKC...

Like us on Facebook

Copyright 2017, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523
Powered by Yodasoft Technologies Pvt. Ltd.