Press Esc to close
Wednesday 03 September 2014
News updated at 12:24 PM IST
Weather
Max: 0°C
Min : 0°C
In Bangalore
Sunny day

Widely prescribed amoxicillin not only useless, harmful too

London, Dec 20, 2012, PTI:

Commonly prescribed antibiotic - amoxicillin - is ineffective for treating coughs and other chest infections, and can be harmful if overused, experts claim.

The overuse of the antibiotic can lead to side effects such as diarrhoea, rash, vomiting and the development of resistance, researchers warned.

“Patients given amoxicillin don’t recover much quicker or have significantly fewer symptoms,” said researcher Paul Little from the University of Southampton.


“Indeed, using amoxicillin to treat respiratory infections in patients not suspected of having pneumonia is not likely to help and could be harmful,” Little said in a statement.

LRTI (chest infections) are one of the most common acute illnesses treated in primary
care in developed countries.

In the study, 2,061 adults with acute uncomplicated LRTI from primary care practices in 12 European countries - including England, the Netherlands, Belgium, Germany, Sweden, France, Italy, Spain and Poland - were randomly assigned to receive either amoxicillin or a placebo three times a day for seven days.

Little difference in severity or duration of symptoms was reported between the two groups. This was true even for older patients aged 60 or more who were generally healthy, in whom antibiotics appeared to have a very limited effect.

Although significantly more patients in the placebo group experienced new or worsening symptoms (19.3 per cent vs 15.9 per cent), the number needed to treat was high (30), and just two patients in the placebo group and one in the antibiotic group required hospitalisation.

Patients taking antibiotics reported significantly more side effects including nausea, rash, and diarrhea, than those given placebo.

“Our results show that most people get better on their own. But, given that a small number of patients will benefit from antibiotics the challenge remains to identify these individuals.” Little said.

Go to Top

Photo Gallery
England's Steven Finn survives a run out attempt

England's Steven Finn survives a run out attempt

President Pranab Mukherjee at Mata Vaishno Devi shrine on Tuesday. J & K Governor NN Vohra is...

President Pranab Mukherjee at Mata Vaishno Devi shrine on Tuesday. J & K Governor NN Vohra is...

India's Ravindra Jadeja celebrates after bowling England's Eoin Morgan

India's Ravindra Jadeja celebrates after bowling England's Eoin Morgan

Shuttler PV Sindhu, bronze medalist at World Badminton Championship, speaking to the media with ...

Shuttler PV Sindhu, bronze medalist at World Badminton Championship, speaking to the media with ...

England's Chris Woakes, right, is run out for 10 runs...

England's Chris Woakes, right, is run out for 10 runs...

Indian cricketer Yuvraj Singh, right, watches Jamaican sprinter Usain Bolt bowl during a...

Indian cricketer Yuvraj Singh, right, watches Jamaican sprinter Usain Bolt bowl during a...

Dhoni And Jos Buttler at the fourth one-day international cricket match...

Dhoni And Jos Buttler at the fourth one-day international cricket match...

A devotee carries a statue of the Hindu god Ganesh, the deity of prosperity, to be immersed into...

A devotee carries a statue of the Hindu god Ganesh, the deity of prosperity, to be immersed into...

Ajinkya Rahane celebrates after scoring a century against England during the fourth One Day...

Ajinkya Rahane celebrates after scoring a century against England during the fourth One Day...

Cricketer Yuvraj Singh presents a bat signed by him to Olympic Gold Medalist sprinter Usain...

Cricketer Yuvraj Singh presents a bat signed by him to Olympic Gold Medalist sprinter Usain...

Copyright 2014, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bangalore - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523