Sunday 20 April 2014
News updated at 3:33 AM IST
Weather
Max: 35°C
Min : 22°C
In Bangalore
Partially cloudy

'Ugly' cholesterol may triple risk of heart disease: study

London, Jan 22 (PTI)

People with high levels of 'ugly' cholesterol face three times increased risk of developing ischemic heart disease, the most common cardiovascular disease.

Cholesterol is divided into 'the good' HDL cholesterol, 'the bad' LDL cholesterol and 'the ugly' cholesterol. It is the so-called 'ugly cholesterol' - also called 'remnant cholesterol' - that can be really harmful.

"LDL cholesterol or 'the bad cholesterol' is of course bad, but our new study reveals that the ugly cholesterol likewise is the direct cause of atherosclerosis resulting in ischemic heart disease and early death," said Professor Borge Nordestgaard from the University of Copenhagen.

"By examining 73,000 persons, we found that an increase in the ugly cholesterol triples the risk of ischemic heart disease, which is caused by lack of oxygen to the heart muscle due to narrowing or blocking of the coronary arteries," he said.


"I hope that this new knowledge will lead to better preventive treatment including lifestyle changes, as more than one in five individuals in affluent countries suffers from high ugly cholesterol," he said.

"We also hope that the pharmaceutical industry will develop new drugs targeted specifically at raised ugly cholesterol levels," he emphasises," he added.

"High ugly cholesterol is the result of high blood levels of normal fat (triglycerides). The most important cause of high ugly cholesterol is overweight and obesity. Persons with high ugly cholesterol should therefore be advised to lose weight, but drugs such as statins and fibrates may also lower levels of ugly cholesterol in the blood," says Borge Nordestgaard.

"To be able to examine the relationship between ugly cholesterol and heart disease, we have used blood samples from persons having a mutation which means that they suffer from high ugly cholesterol their entire life," said researcher Anette Varbo.

"The research findings do therefore not depend on their lifestyle patterns in general. Unhealthy lifestyle factors such as smoking, fatty foods and overweight all increase the risk of heart disease, and the blood samples from persons having these mutations thus give the most accurate results," Varbo added.

The study was published in the Journal of the American College of Cardiology.

Go to Top

Photo Gallery
Actor-Director Farhan Akhtar along with Rahul Bose and Ronnie Lahiri during the inauguration ...

Actor-Director Farhan Akhtar along with Rahul Bose and Ronnie Lahiri during the inauguration ...

During the extended week end, large number of tourists flock to Amba vilas palace, in Mysore. DH...

During the extended week end, large number of tourists flock to Amba vilas palace, in Mysore. DH...

A farmer trying to drain out water from his wheat field with the help of a bucket after heavy...

A farmer trying to drain out water from his wheat field with the help of a bucket after heavy...

Rickshaw pullers try to keep their balance as they ride past a dust storm in Agartala, Saturday...

Rickshaw pullers try to keep their balance as they ride past a dust storm in Agartala, Saturday...

People drinking coconut water on a hot summer day near VV Mohall, in Mysore. DH photo

People drinking coconut water on a hot summer day near VV Mohall, in Mysore. DH photo

Transgenders celebrate the Supreme Court's verdict recognising transgenders or eunuchs as third...

Transgenders celebrate the Supreme Court's verdict recognising transgenders or eunuchs as third...

School children paint on the body of a tram during the 'World Art day' celebrations in Kolkata on...

School children paint on the body of a tram during the 'World Art day' celebrations in Kolkata on...

Shuttler Saina Nehwal with students at a promotional event in Hyderabad on Saturday. PTI Photo

Shuttler Saina Nehwal with students at a promotional event in Hyderabad on Saturday. PTI Photo

Children participating in the drawing and patinting competition, organised by Manjushri arts and...

Children participating in the drawing and patinting competition, organised by Manjushri arts and...

Police and locals remove rubbles from a vehicle damaged after landslide on Jammu-Srinagar ...

Police and locals remove rubbles from a vehicle damaged after landslide on Jammu-Srinagar ...

Copyright 2014, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bangalore - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523