Press Esc to close
Tuesday 28 June 2016
News updated at 11:27 AM IST
Weather
Max: 27.2°C
Min : 20.8°C
In Bengaluru
Rain lightly

Lack of sleep can alter gene activity

London, Feb 27, 2013, PTI:

Just one week of inadequate sleep is enough to alter the activity of over 700 human genes, a new study has warned.

University of Surrey researchers monitored the activity of all genes of the human genome and found that inadequate sleep (less than 6 hours a night) affects the activity of hundreds of our genes.

These included genes which are linked to controlling inflammation, immunity, and the response to stress.

The research also showed that inadequate sleep reduced the number of genes that normally peak and wane in expression throughout the 24-hour day from 1,855 to 1,481.
Researchers found that the number of genes affected by sleep deprivation was seven times higher after a week of insufficient sleep.

Sleep deficiency leads to a host of significant health conditions including obesity, heart disease, and cognitive impairment, but until now scientists were unclear how gene expression patterns were altered by insufficient sleep.

These ‘gene expression’ patterns provide important clues on the potential molecular mechanisms linking sleep and overall health.

“This research has helped us to understand the effects of insufficient sleep on gene expression. Now that we have identified these effects we can use this information to further investigate the links between gene expression and overall health,” Derk-Jan Dijk, Director of the Sleep Research Centre at the University of Surrey, said in a statement.

“The current interest in sleep and circadian rhythms as determinants of health and disease is a vital area of research,” said Colin Smith, Professor of functional genomics at the University of Surrey.

“By combining our expertise in sleep and ‘genomics’ (the study of the full complement of our genes), we are starting to make breakthroughs that will have an impact on our understanding and treatment of poor health arising from insufficient sleep,” Smith added.


Go to Top

Photo Gallery
People carry an effigy representing inflation devil on a camel-cart during a demonstration...

People carry an effigy representing inflation devil on a camel-cart during a demonstration...

A car wades through a water logged lane at Jayadev Bihar after heavy monsoon rains in Bhubaneswar...

A car wades through a water logged lane at Jayadev Bihar after heavy monsoon rains in Bhubaneswar...

A sadhu at a base camp for Amarnath Yatra ahead of their registration in Jammu...

A sadhu at a base camp for Amarnath Yatra ahead of their registration in Jammu...

The titular head of Wodeyar dynasty Yaduveer Krishnadatta Chamaraja Wodeyar and Trishika Kumari...

The titular head of Wodeyar dynasty Yaduveer Krishnadatta Chamaraja Wodeyar and Trishika Kumari...

A white tiger takes bath in a pond during a hot summer day at its enclosure in Kolkata Zoo...

A white tiger takes bath in a pond during a hot summer day at its enclosure in Kolkata Zoo...

An artiste gives finishing touches to an idol of Goddess Durga for upcoming Durga Puja...

An artiste gives finishing touches to an idol of Goddess Durga for upcoming Durga Puja...

Collapsed tents at BJP Awadh Kshetriya Booth Sammelan following the storm, in Barabanki...

Collapsed tents at BJP Awadh Kshetriya Booth Sammelan following the storm, in Barabanki...

Women Kabaddi players who will take part in the Women's Kabaddi Challenge, at a press conference...

Women Kabaddi players who will take part in the Women's Kabaddi Challenge, at a press conference...

People enjoy the rainy weather on a beach along the Arabian Sea in Mumbai...

People enjoy the rainy weather on a beach along the Arabian Sea in Mumbai...

The underconstruction Bogibeel Bridge over the mighty Brahmaputra River in Dibrugarh district....

The underconstruction Bogibeel Bridge over the mighty Brahmaputra River in Dibrugarh district....

Copyright 2014, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523