Spain, Germany have it easy
England moved level on points at the top of Group H with Montenegro after marching to a 4-0 home win over Moldova that came as their rivals were held 1-1 in Poland.
Italy and Belgium were among the group pacesetters to take full points, while Group E leaders Switzerland could only draw 4-4 with Iceland and Group G table-toppers Bosnia surprisingly lost 1-0 at home to Slovakia.
In Belfast, Portugal were in serious danger of being knocked off the top of Group F, after second-placed Russia had earlier thumped Luxembourg 4-1, as they found themselves trailing 2-1 to Northern Ireland.
Their hosts had previous form for upsets having stunned Russia 1-0 last month and it looked like they were heading for another when Portugal's Helder Postiga was shown a straight red card for a headbutt on Gareth McAuley just before half-time.
Northern Ireland, already out of qualifying contention, made the man advantage count early in the second half when Jamie Ward scored after a corner but Portugal's fortunes turned when Kevin Brunt was shown a second yellow to make it 10 against 10.
Then followed 15 minutes of trademark Ronaldo brilliance as he headed in two goals and scored another from a freekick to turn the match around and put Portugal on 17 points from eight games with Russia on 15 having played one game fewer.
Evergreen forward Miroslav Klose netted once again as Germany coasted to s 3-0 win over Austria in Group C.
The clean sheet banished concerns over recent German defensive frailties as they stayed in control of the group on 19 points from seven matches, five ahead of Sweden who beat Ireland 2-1. Austria dropped to third on 11, level with the Irish.
Netherlands also had defensive questions to answer after they saw a first-minute lead secured by Arjen Robben evaporate in Tallinn where they stood seconds away from an embarrassing 2-1 defeat after a Konstantin Vassiljev double for the hosts.
Spirits were much higher at Wembley where England outclassed Moldova after two goals from Danny Welbeck and one each from captain Steven Gerrard and Rickie Lambert propelled Roy Hodgson's side to the top of Group H on goal difference.
World champions Spain were 2-0 winners in Finland as they tightened their grip on top spot in Group I, with their cause helped by second-placed France's 0-0 draw in Georgia.