Press Esc to close
Friday 22 September 2017
News updated at 11:38 AM IST

Ghostwriters overstate drug benefits, downplay flip side

Last updated: 13 September, 2010
Washington, Sep 13 (IANS): 16:48 IST

Ghostwritten articles overstate benefits of hormone replacement therapy and downplay its flip side.

The first analysis of the 1,500 documents, unsealed in recent litigation against pharma giant Wyeth (now part of Pfizer), reveals unprecedented insights into how such companies use ghostwriters to insert marketing messages into articles published in medical journals.

Adriane Fugh-Berman, associate professor at the Georgetown University Medical Center in Washington DC, analysed dozens of ghostwritten reviews and commentaries published in medical journals and journal supplements.
They were used to promote unproven benefits and downplay harms of Prempro -- a brand of menopausal hormone therapy (HT) -- and to cast competing therapies in a negative light.

These articles were widely circulated to medical representatives and doctors to disseminate the company's marketing messages, reports the journal Public Library of Science.

Wyeth used a medical education and communication company, DesignWrite, to produce ghostwritten articles in order to mitigate the perceived risks of breast cancer associated with menopausal hormone therapy, according to a Georgetown University release.
The analysis revealed that DesignWrite was paid $25,000 to ghostwrite articles reporting clinical trials, including four manuscripts on the trials of low-dose Prempro.

DesignWrite was also assigned to write 20 review articles about the drug, for which they were paid $20,000 each.

The analysis concludes: "Given the growing evidence that ghostwriting has been used to promote HT and other highly promoted drugs, the medical profession must take steps to ensure that prescribers renounce participation in ghostwriting, and to ensure that unscrupulous relationships between industry and academia are avoided rather than courted."

Go to Top

Photo Gallery
Vehicles wade through a flooded road after heavy rains in Thane district of Maharashtra on...

Vehicles wade through a flooded road after heavy rains in Thane district of Maharashtra on...

Real Madrid's Cristiano Ronaldo closes his eyes during Spanish the La Liga soccer match between...

Real Madrid's Cristiano Ronaldo closes his eyes during Spanish the La Liga soccer match between...

A woman covers herself with a plastic bag as she makes her way to work as Hurricane Maria...

A woman covers herself with a plastic bag as she makes her way to work as Hurricane Maria...

An artisan applies finishing touches on an idol of the Hindu goddess Durga, before it is...

An artisan applies finishing touches on an idol of the Hindu goddess Durga, before it is...

Bollywood actress Nidhhi Agerwal showcases a creation by designer Rajat K Tangri during the...

Bollywood actress Nidhhi Agerwal showcases a creation by designer Rajat K Tangri during the...

People pushing a car at a waterlogged road after heavy rains in Varanasi on Thursday...

People pushing a car at a waterlogged road after heavy rains in Varanasi on Thursday...

Policemen guard outside former chief minister S M Krishna's son in-law Siddartha's corporate ...

Policemen guard outside former chief minister S M Krishna's son in-law Siddartha's corporate ...

Indian players celebrate the dismissal of Australia's David Warner...

Indian players celebrate the dismissal of Australia's David Warner...

Actor Kamal Haasan with Aam Aadmi Party (AAP) chief and Delhi Chief Minister Arvind Kejriwal...

Actor Kamal Haasan with Aam Aadmi Party (AAP) chief and Delhi Chief Minister Arvind Kejriwal...

A man is rescued from a collapsed building in the Condesa neighborhood of Mexico City after an...

A man is rescued from a collapsed building in the Condesa neighborhood of Mexico City after an...

Like us on Facebook

Copyright 2017, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523
Powered by Yodasoft Technologies Pvt. Ltd.