Late goals gave Liverpool a 2-0 home win over 10-man Inter Milan while Roma came from behind to beat Real Madrid 2-1 as the Champions League resumed after its nine-week winter break on Tuesday.
In other last 16 first-leg matches, Germany’s Schalke beat 2004 winners Porto 1-0 in Gelsenkirchen while Chelsea were held to a 0-0 draw at Greek champions Olympiakos Piraeus in Athens.
Inter’s packed defence held out in the first half after having Marco Materazzi sent off in the 30th minute for two yellow cards, but the Serie A leaders cracked in the closing stages after relentless pressure from the 2005 winners. Dutchman Kuyt finally broke the deadlock in the 85th minute with a downward volley that bounced wickedly over the outstretched arms of ’keeper Julio Cesar.  Gerrard delighted the Anfield faithful in the final minute of regular time when he drilled in a crisp low shot from 25 metres that beat Cesar all the way at the far post.
Raul gave Real a perfect start in the eighth minute when he turned in a speculative shot by Guti after Arjen Robben’s darting run and cross from the left.
David Pizarro drew Roma level midway through the first half with a deflected effort after Totti had fed Mancini and the Brazilian played the ball into his path.
Mancini grabbed the winner shortly before the hour with a cool finish, having rounded the ’keeper after Totti won a loose ball in midfield and put him through.
Chelsea held on to a goalless draw with captain John Terry and England midfielder Frank Lampard starting on the bench.