Research: New technique developed for clearer fatty liver observation

Health issues related to obesity can take many different forms. Obese people are more likely to have nonalcoholic steatohepatitis (NASH), a kind of fatty liver disease that can lead to cancer.

The lack of appropriate and effective techniques to separate and characterise hepatic stellate cells (HSCs), which have been shown to play a key role in the advancement of liver fibrosis and liver cancer in NASH patients, has contributed to the lack of treatment for NASH.

With their novel method of performing cold enzymatic perfusion to separate HSCs from both murine and human fatty liver-associated malignancies, researchers from Osaka Metropolitan University made a significant advancement in their quest.

Cellular and Molecular Gastroenterology and Hepatology published this research.