<p>According to a study, 5 alpha reductase inhibitors found in such drugs interfere with the effect of certain male hormones (androgens) on the prostate.<br /><br />Researchers led by Abdulmaged M. Traish of Boston University School of Medicine examined data reported from available literature concerning the side effects of the 5 alpha reductase inhibitors, finasteride and dutasteride. <br /><br />Prolonged adverse side effects on sexual function, depression and diminished libido were reported by a subset of men, The Journal of Sexual Medicine reports.<br /><br />Drug-related reduction in libido occurred in 4.2 percent and 1.8 percent of patients in the dutasteride and placebo groups respectively. <br /><br />Reduced ejaculation and semen volume were also reported. In some patients, these drugs were associated with depression, according to a Boston University statement.<br /><br />"For these reasons, patients and doctors are urged to discuss these issues openly and candidly and assess the risk benefit ratio prior to commencing therapy with 5 a-reductase inhibitors," Traish noted.</p>
<p>According to a study, 5 alpha reductase inhibitors found in such drugs interfere with the effect of certain male hormones (androgens) on the prostate.<br /><br />Researchers led by Abdulmaged M. Traish of Boston University School of Medicine examined data reported from available literature concerning the side effects of the 5 alpha reductase inhibitors, finasteride and dutasteride. <br /><br />Prolonged adverse side effects on sexual function, depression and diminished libido were reported by a subset of men, The Journal of Sexual Medicine reports.<br /><br />Drug-related reduction in libido occurred in 4.2 percent and 1.8 percent of patients in the dutasteride and placebo groups respectively. <br /><br />Reduced ejaculation and semen volume were also reported. In some patients, these drugs were associated with depression, according to a Boston University statement.<br /><br />"For these reasons, patients and doctors are urged to discuss these issues openly and candidly and assess the risk benefit ratio prior to commencing therapy with 5 a-reductase inhibitors," Traish noted.</p>