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Cure for jet lag may finally be here!

Scientists are one step closer to make jet lag and shift work less painful, as they have discovered the body clock “reset button”.

The findings could reduce the symptoms of travelling through different time zones and working unsociable hours, which often makes people either tired or unable to sleep, the Independent reported.

Results from the study suggest that the newly-found button could be used to switch the master clock to a new time zone, for example from London to Beijing, in just one day.

A team based at Kyoto University in Japan discovered the “reset button” in the brain.

There are clocks located throughout the body but the master clock is found within the brain, where it works to keep the body in tune with the world around us, creating fatigue at night and alertness during daylight.

The clock uses light to monitor time, but adjusts slowly. For every time zone travelled, it takes the body approximately a full day to catch up, according to the BBC.

The team, led by Yoshiaki Yamaguchi, examined genetically modified mice with no vasopressin receptors and found they were able to re-adjust clocks that have been put back eight days within one day.

New norovirus vaccine cuts symptoms of illness by50 pc

An investigational vaccine seems to be effective against the most common strain of norovirus, and has been found to reduce the main symptoms of the gastrointestinal (GI) infection, vomiting and/or diarrhea, by 52 per cent, a research has suggested.

Currently, there is no treatment or cure for norovirus, the most common cause of severe GI infection in the US.

Lead author David I. Bernstein, MD, MA, professor of pediatrics at Cincinnati Children’s Hospital Medical Center and the University of Cincinnati, said that norovirus truly is a global issue and most if not everyone has experienced it to some degree.

The randomized, multi-center study included 98 people who agreed to drink water containing a significant dose of the virus, 50 who received the injected vaccine and 48 who received a placebo injection that did not contain the vaccine.

Neither the participants nor the researchers knew in advance who received the vaccine and who did not. In the vaccine group, 26 (52 per cent) were infected, as were 29 (60 per cent) of those in the non-vaccine group.

In people who received the vaccine, 10 (20 per cent) suffered from mild, moderate or severe vomiting and/or diarrhea versus 20 (42 per cent) in the non-vaccine group, a 52 per cent reduction in symptoms.

How specific ‘high fat’ diet can actually help fight obesity

A new research has found that a diet high in a certain type of fat may actually increase metabolism.

After studying genetically modified mice, the discovery by Texas Tech University nutrition scientists could lead to supplements and a diet regime that will increase metabolism and decrease muscle fatigue in humans.

Chad Paton, an assistant professor of nutritional biochemistry in the Department of Nutrition, Hospitality and Retailing, said that he and his colleagues were curious why skeletal muscles of obese people contained a certain type of enzyme that breaks down saturated fats.

To test what that enzyme did, Paton’s lab and colleagues from the University of Wisconsin – Madison genetically modified mice so that their muscles would constantly produce the enzyme.

“We used a transgenic mouse model, and we took the gene that makes the enzyme that’s not normally expressed and took away it’s regulation to make it active all the time,” Paton said.

“What we found in those animals is they had a hypermetabolic rate compared to the wild mice, increased energy consumption and greatly increased these animals’ exercise capacity,” he said.

The enzyme, called SCD1, converts saturated fat into monounsaturated fat, which is easier to metabolize. The liver will produce this enzyme depending on the fat content of the food consumed, he said. Fatty adipose tissue produces it all the time as a way of regulating itself.

Only in heavily exercised muscle tissue or in the case of obesity does skeletal muscle produce the enzyme, he said.

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