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How stress leads to heart attack

A new study has revealed the hypothetical mechanism behind heart attack caused by stress, emotional shock, or overexertion.

Hormones released during stressful situations appear to cause bacterial biofilms on arterial walls to disperse, allowing plaque deposits to rupture into the bloodstream that leads to heart attack.

David Davies of Binghamton University said that their hypothesis fitted with the observation that heart attack and stroke often occur following an event where elevated levels of catecholamine hormones are released into the blood and tissues, such as occurs during sudden emotional shock, stress or over-exertion.

He further explained that at least one species of bacteria ‘Pseudomonas aeruginosa’ commonly associated with carotid arteries in their studies, was able to undergo a biofilm dispersion response when exposed to norepinephrine, a hormone responsible for the fight-or-flight response in humans.

This research suggests that bacteria should be considered to be part of the overall pathology of atherosclerosis and management of bacteria within an arterial plaque lesion may be as important as managing cholesterol.The research is published in mBio.
New discovery could soon make leukemia history

The researchers in Australia are close to finding a promising new way to get rid of the leukemia cancer cells in patients.

Researchers from South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaid’s Centre for Personalised Cancer Medicine, have found that cancer cells decide whether to live or die after a short period of intense exposure to targeted therapy, opposing the current requirement for continuous treatment.

Professor Deborah White, Director, Cancer Research with SAHMRI and University of Adelaide professor said that the discovery is paradigm shifting and the findings are not just applicable to chronic myeloid leukemia (CML) therapy, but to all targeted cancer treatments.

She added that they were looking for methods that will result in the cancer cell killing itself, which would provide an improved treatment and reduce the risk of cancer relapse.

Lisa Schafranek, University of Adelaide PhD student, who had been investigating the role of a common protein known as STAT5 with Professor White and her research team, said added that the activity of the protein appeared to be a critical determinant of the decision for cancer cells to live or die, and their research found that by blocking STAT5 in conjunction with exposure to a regular anti-cancer treatment, they were able to target the leukemia cells more effectively.

The results have been published online ahead of print in the journal Leukemia.
Eating oatmeal can help you feel full longer: Study

A new research has revealed that eating one bowl of instant oatmeal for breakfast helps to manage hunger better than the same amount of leading oat-based cereal.

The statistically significant results established that instant oatmeal enhanced satiety, feelings of fullness and reduced the desire to eat more than a RTE, oat-based cereal.Frank Greenway, M.D. said that instant oatmeal is more effective at suppressing appetite compared to the cold cereal, even with a smaller serving size and less calories than previously investi-gated.

Marianne O’Shea, PhD, PepsiCo R and D Nutrition revealed that something as simple as a single-serving of instant oatmeal and milk has the potential to help keep hunger at bay from breakfast until lunch.

The study also supports the mission at the Quaker Oats Center of Excellence of investigating the ways that oats can improve our health and well-being, she added.

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