Italy's Gregorio Paltrinieri won the world 1500M freestyle title on Sunday after China's world record holder Sun Yang was a shock withdrawal from the final.
Paltrinieri clocked 14:39.67 seconds to claim gold with Connor Jaeger of the United States taking silver at 1.53 seconds, while Canada's Ryan Cochrane was third at 11.41.
Sun later confirmed his shock withdrawal was down to a heart problem.
The 23-year-old said he made the decision to pull out shortly before being called to the pool having felt unwell during the warm-up.
The Chinese explained he started feeling problems with his heart after retaining his 800M freestyle world title on Wednesday.
Australia's Bronte Campbell won the women's 50M freestyle final to complete the sprint double having already won the 100m title.
The 21-year-old clocked 24.12 seconds to take gold with Ranomi Kromowidjojo of the Netherlands taking silver at 0.10 seconds back as Sweden's Sarah Sjostrom earned bronze at 0.19.
Hungary's Katinka Hosszu completed the individual medley double on Sunday with victory in the women's 400M final having already claimed the 200M crown.
Hosszu touched the wall at 4:30.29 seconds, with Maya di Rado of the United States claiming second at 1.32 seconds with Emily Overholt of Canada taking bronze at 2.13.
Sweden's Jennie Johansson was the shock winner of the women's 50M breaststroke gold .
Johansson clocked 30.05 to win on the wall as Jamaica's Alia Atkinson claimed silver at just 0.06 seconds back while Russia's Yuliya Efimova, the 100M champion, earned bronze at 0.08.
France's Camille Lacourt won the men's 50M backstroke final.
Lacourt clocked 24.23 seconds to claim gold with Matt Grevers of the USA taking silver at 0.38 seconds back while Ben Treffers of Australia earned bronze at 0.46.
Meanwhile, Japan's Daiya Seto won the men's 400M individual medley final.
Seto clocked four minutes, 08.50 seconds to claim gold with Hungary's David Verraszto taking silver at 1.40 seconds back as Chase Kalisz of the United States earned bronze at 1.55. As expected, the US won the men's 4x100M medley relay gold.
The US quartet clocked 3:29.93 seconds to win gold on the wall with Australia taking silver at 0.15 back while defending champions France had to settle for bronze at 0.57.
China claimed women's 4x100M medley relay final.
The Chinese quartet clocked three minutes, 54.41 seconds to claim gold with Sweden taking silver at 0.83 seconds with Australia earning bronze at 1.15 back.
Serbia won their second world water polo championship as an independent nation in an 11-4 rout of traditional rivals Croatia in the final.
Results: Men: 1500M Freestyle: Gregorio Paltrinieri (Ita) 14:39.67, 1; Connor Jaeger (US) 14:41.20, 2; Ryan Cochrane (Can) 14:51.08, 3.
50M Backstroke: Camille Lacourt (Fra) 24.23, 1; Matthew Grevers (US) 24.61, 2; Benjamin Treffers (Aus) 24.69, 3.
400M Individual Medley: Daiya Seto (Jap) 4:08.50, 1; David Verraszto (Hun), 4:09.90, 2; Chase Kalisz (US) 4:10.05, 3.
4 x 100M Medley Relay: US 3:29.93, 1; Australia 3:30.08, 2; France 3:30.50, 3.
Women: 50M Freestyle: Bronte Campbell (Aus) 24.12, 1; Ranomi Kromowidjojo (Ned) 24.22, 2; Sarah Sjoestroem (Swe) 24.31, 3.
50M Breaststroke: Jennie Johansson (Swe) 30.05, 1; Alia Atkinson (Jam) 30.11, 2; Yuliya Efimova (Rus) 30.13, 3.
400M Individual Medley: Katinka Hosszu (Hun) 4:30.39, 1; Maya DiRado (US) 4:31.71, 2; Emily Overholt (Can) 4:32.52, 3.
4x100M Medley relay: China (3:54.41) 1; Sweden (3:55.24) 2; Australia (3:55.56) 3.