Microneedles may make getting flu shots easier

Patient friendly

That’s right, tiny little needles so small you don’t even feel them. Attached to a patch like a Band-Aid, the little needles barely penetrate the skin before they dissolve and release their vaccine.

Researchers led by Mark Prausnitz of Georgia Institute of Technology reported their research on microneedles in Sunday’s edition of Nature Medicine. The business side of the patch feels like fine sandpaper, he said.

In the Georgia Tech work, the vaccine is still injected. But the needles are so small that they don’t hurt and it doesn’t take any special training to use this kind of patch.
So two problems are solved right away — fear of needles, and disposal of leftover hypodermic needles.

Painless vaccination
“The goal has been a means to administer the vaccine that is patient friendly,” Mark R Prausnitz of Georgia Tech said. That means “not only not hurting or looking scary, but that patients could self-administer,” he said, and people would be more likely to get the flu vaccine.

By developing needles that dissolve, there are no leftover sharp needles, especially important for people who might give themselves the vaccine at home, he said.

The researchers are now seeking funds to begin tests in people and, if all goes well, the patch could be in use in five years, he said.

Flu vaccination is recommended for nearly everyone, every year, and that’s a big burden on the public health network, Prausnitz noted. Many people don’t get the shot because it’s inconvenient, but if they could get in mail or at the pharmacy they might do so, he said.

The patch is placed on the skin and left for 5 minutes to 15 minutes, he said. It can remain longer without doing any damage, he said.

 Asked if the term “microneedle” might still frighten some folks averse to shots, Prausnitz said he was confident that marketers would come up with a better term before any sales began.

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