First human case of rat disease found in HK

A Hong Kong man has developed the world’s first ever human case of the rat version of the hepatitis E virus, according to new research from one of the city’s leading universities.

There had previously been no evidence the disease could jump from rats to humans, the University of Hong Kong said Friday, warning the discovery had “major public health significance”. 

“This study conclusively proves for the first time in the world that rat HEV can infect humans to cause clinical infection,” the university added. Rat hepatitis E virus is very distantly related to human hepatitis E virus variants, HKU said. 

The disease was found in a 56-year-old man who persistently produced abnormal liver function tests following a liver transplant. He could have contracted the illness through food infected by rat droppings, researchers said, according to details of the findings reported in the South China Morning Post.

The man lived in a housing estate where there were signs of rat infestation outside his home. He is now recovering after being treated for the virus, the SCMP added. The human version of hepatitis E is a liver disease that affects 20 million people globally each year, according to the World Health Organisation.