Mathematical model decodes

Asymmetric cell division

Cell division

An interdisciplinary study by scientists from IIT-Bombay and the Francis Crick Institute, London, has attempted to understand and model the role of asymmetry in the process of cell division in eukaryotic cells — cells with a nucleus enclosed within a membrane — using the roundworm (Caenorhabditis elegans) embryo.

Researchers have developed a mathematical model that explains this asymmetrical phenomenon of cell division. They predict that the force exerted on the cell membrane by proteins like anillin and septin, during cell division, is the primary reason behind the asymmetric ring closure. They further add that if these proteins flow towards the ring symmetrically, they can force the asymmetrical ring to close symmetrically. It’s just like trying to crush a can of coke. If you apply equal pressure with all your fingers on the can, it gets evenly crushed from all sides. But, if you crush it using pressure from only one side, there will be a depression on only one side.

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Mathematical model decodes

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