'Covishield 81% effective at preventing severe Covid'

Covishield 81% effective at preventing severe Covid-19 infection: Study

It's one of the first Indian studies conducted to test Covishield’s efficacy during the Delta strain dominated second wave

Representative image. Credit: AFP File Photo

In a new study, Serum Institute of India’s (SII) Covishield has shown 63 per cent overall efficacy rate and 81 per cent efficacy in preventing severe Covid-19 infections in fully vaccinated people.

It's one of the first Indian studies conducted to test Covishield’s efficacy during the Delta strain dominated second wave, according to The Economic Times report. This preprint study is under submission to The Lancet.

Translational Health Science and Technology, Faridabad along with CSIR- Institute of Genomics and Integrative Biology, National Institute of Immunology and the Indian Consortium of Covid-19 research, worked on this study.

Read | Covid-19 vaccine inequity: Inside the cutthroat race to secure doses

According to the study, the cell mediated immunity, despite the ability of Delta strain to reduce antibody-led immune response.

As the study shows that complete vaccination with Covishield has successfully protected people from severe Covid-19 infection, it encourages people to get both the doses of the vaccine.

However, it added that there was a significant drop in antibody-led immune response to the Delta variant but the cell mediated immunity was maintained in the Covishield vaccine recipients. It also mentions that protection against severe infection is due to cell mediated immunity.

Read | Indonesia is the new epicentre of the Covid-19 pandemic

The study was conducted between April 1 to May 31, on 2,766 individuals who were affected by the Delta variant.

It also mentioned that the T-cell responses were preserved against the recombinant mutant receptors. The T-cells helped in binding domain antigens to push for cell-mediated immune response to the Delta virus.

Get a round-up of the day's top stories in your inbox

Check out all newsletters

Get a round-up of the day's top stories in your inbox