Malaga stay strong at fourth
Martin Demichelis and Eliseu, with a penalty, earned Malaga the points as they were helped by a red card for Sevilla defender Federico Fazio in the 69th minute.
Malaga, who have qualified for the last-16 of the Champions League in their debut campaign, moved on to 28 points from 16 games, four behind third-placed Real Madrid.
Sevilla paid dearly for failing to convert early pressure into goals, in particular striker Alvaro Negredo who rounded the Malaga keeper only to fire against the post in the third minute.
Malaga scored with almost their first attempt just after halftime when Argentina defender Demichelis looped a header back under the bar at a corner, and Sevilla struggled to react.