Sevilla nail Deportivo
Sevilla sacked coach Michel and replaced him with Unai Emery in January and have now won three of their five league games since he took charge.
They are in 10th place on 32 points, five off the European berths.
Croatia midfielder Ivan Rakitic headed the Andalusian side in front after five minutes at the Sanchez Pizjuan stadium although the ball appeared to brush Medel's hand on its way into the net.
The Chilean doubled the home side's lead in the 27th when he turned in a Jesus Navas cross before Riki pulled a goal back for Depor five minutes later.
Medel, a defensive midfielder who rarely gets on the scoresheet, clipped home his second goal in the 40th and Sevilla goalkeeper Beto then pulled off a couple of fine saves in the second half to deny Depor a way back into the match.