Press Esc to close
Tuesday 25 April 2017
News updated at 6:04 PM IST

Scientists develop nanoparticles for diabetics

Boston, May 4, 2013, IANS : 16:57 IST
File Image.

US researchers have engineered nanoparticles for diabetics capable of releasing insulin in the blood thereby to help maintain normal blood sugar levels, says a study.

In a promising development for diabetes treatment, researchers have developed a network of nanoscale particles that can be injected into the body and release insulin when blood-sugar levels rise, maintaining normal blood sugar levels for more than a week in animal-based laboratory tests.

The work was done by researchers at North Carolina State University, the University of North Carolina at Chapel Hill, the Massachusetts Institute of Technology and Children's Hospital Boston, reports Science Daily.

"We've created a 'smart' system that is injected into the body and responds to changes in blood sugar by releasing insulin, effectively controlling blood-sugar levels," says Dr. Zhen Gu, lead author of a paper describing the work and an assistant professor in the joint biomedical engineering program at NC State and UNC Chapel Hill.

"We've tested the technology in mice, and one injection was able to maintain blood sugar levels in the normal range for up to 10 days."

The new, injectable nano-network is composed of a mixture containing nanoparticles with a solid core of insulin, modified dextran and glucose oxidase enzymes.

When the enzymes are exposed to high glucose levels they effectively convert glucose into gluconic acid, which breaks down the modified dextran and releases the insulin.

The insulin then brings the glucose levels under control. The gluconic acid and dextran are fully biocompatible and dissolve in the body.

Each of these nanoparticle cores is given either a positively charged or negatively charged biocompatible coating.

The positively charged coatings are made of chitosan (a material normally found in shrimp shells), while the negatively charged coatings are made of alginate (a material normally found in seaweed).

Go to Top

Photo Gallery
Injured CRPF being brought to Raipur for treatment on Monday follwing a Maoist attack at Burkapal ..

Injured CRPF being brought to Raipur for treatment on Monday follwing a Maoist attack at Burkapal ..

Police in action students who were throwing brick bats on them during clashes in the vicinity of ...

Police in action students who were throwing brick bats on them during clashes in the vicinity of ...

LJP activists take part in a candle light vigil to pray for CRPF jawans lost their lives in a ...

LJP activists take part in a candle light vigil to pray for CRPF jawans lost their lives in a ...

Remains of the iconic Hall of Nations structure at Pragati Maidan in New Delhi on Monday...

Remains of the iconic Hall of Nations structure at Pragati Maidan in New Delhi on Monday...

Cricketer Sachin Tendulkar being greeted by his fans on his 44th birthday at his residence in Mumbai

Cricketer Sachin Tendulkar being greeted by his fans on his 44th birthday at his residence in Mumbai

Girl students pelt stones at security personnel during clashes in the vicinity of Lal Chowk in ...

Girl students pelt stones at security personnel during clashes in the vicinity of Lal Chowk in ...

College girls shout slogans at a protest against the recent police action on students, in Srinagar..

College girls shout slogans at a protest against the recent police action on students, in Srinagar..

Potato farmers holding a protest over their various demands including proper cold storage ...

Potato farmers holding a protest over their various demands including proper cold storage ...

A man holds his head in despair after grains got drenched in rains at a market in Bikaner on ...

A man holds his head in despair after grains got drenched in rains at a market in Bikaner on ...

Woakes jubiliate with his teammates after the dismissal of Stuart Binny

Woakes jubiliate with his teammates after the dismissal of Stuart Binny

Like us on Facebook

Copyright 2017, The Printers (Mysore) Private Ltd., 75, M.G Road, Post Box 5331, Bengaluru - 560001
Tel: +91 (80) 25880000 Fax No. +91 (80) 25880523
Powered by Yodasoft Technologies Pvt. Ltd.