The accident occurred Sunday morning in the Andean region of Ecuador, Xinhua reported.
Most of the injured were in serious conditions and had been taken to nearby hospitals.
The bus was traveling from Cuenca, in the centre of the country, to the capital Quito.
The latest toll has not been confirmed by the police. Earlier, Ecuadorian Interior Minister Gustavo Jalkh said 38 people died in the accident.
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