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Eating low-calorie diet for four months 'can cure diabetes'
PTI
Last Updated IST

A team at Leiden University in the Netherlands says its findings may revolutionise the treatment of the lifelong condition with no cure, and caused by pancreas not producing enough insulin to break down glucose in the blood.

In their study, researchers found that diabetics who slashed the calories they ate each day actually had a far more significant improvement in the condition and in their general health than medication offered.

They no longer needed life-saving insulin, the level of dangerous fat built up around their hearts was significantly reduced and their cardiac function improved.

"It is striking to see how a relatively simple intervention of a very low-calorie diet effectively cures Type 2 diabetes. Moreover, the effects are long term, illustrating the potential of this method.

"Lifestyle interventions may have more powerful beneficial cardiac effects than medication in these patients," the 'Daily Express' quoted the study's lead author Sebastiaan Hammer as saying.

The discovery has major implications as diabetics and the obese are particularly at risk of suffering a potentially fatal heart attack or being struck down by debilitating heart disease, say the researchers.

In their study, the researchers wanted to discover long- term effects of weight loss by restricting calorie intake.

Pericardial fat is a build-up around the heart that can stop it from working properly, particularly in the obese and sufferers from metabolic disease seen as a precursor to heart disease.

Dr Hammer said: "Our results show that 16 weeks of caloric restriction improved heart function in these patients. More importantly, despite regain of weight, these beneficial cardiovascular effects were persistent over the long term."

Using scans, the researchers analysed heart function and pericardial fat in 15 patients -- seven men and eight women -- with Type 2 diabetes before and after four months of a diet consisting of 500 calories a day.

Changes in body mass index (BMI) were also measured. The results showed that caloric restriction reduced BMI from 35.3 to 27.5 over four months. Pericardial fat also decreased by about a third and resting heart function improved noticeably.

And, after an additional 14 months of follow-up on a regular diet, BMI increased to 31.7, but pericardial fat only increased slightly. On average, someone who has a BMI of 30 will get diabetes.

Experts have welcomed the findings.

Dr Lorna Layward, a spokeswoman for the Stroke Association said: "Diabetes, being overweight and poor heart function can all increase our risk of stroke. Losing weight is something that everybody can do something about and it can have a huge impact on improving our overall health."

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(Published 29 November 2011, 14:11 IST)