Sheikh Fateh had reportedly been given the job in May after Al-Qaeda's purported number three and Osama bin Laden's one-time treasurer Mustafa Abu al-Yazid was killed.
Pakistani security officials said the Egyptian was killed on Saturday in a US drone strike on North Waziristan, a hub of Al-Qaeda and Taliban commanders where the covert American missile war has been concentrated.
"Yes, he has been killed," one Pakistani security official told AFP on condition of anonymity.
Two other Pakistani intelligence officials confirmed his death.
"He was head of Al-Qaeda in Afghanistan and Pakistan," one official said. Locally, he was known as Abdul Razzaq, the official added.
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