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Bengaluru: Bengaluru-based cardiologist Dr H S Natraj Setty has garnered global recognition for his pioneering research on cardiac complications in HIV patients. His study, titled ‘Cardiac Complications in People Living With HIV: Long-Term Insights From an Indian Cohort’ was presented at the Transcatheter Cardiovascular Therapeutics (TCT), 2025 conference held in San Francisco, USA, and the study was published in the Journal of the American College of Cardiology (JACC).
The research represents one of India's largest long-term studies on HIV-associated coronary artery disease, encompassing 910 patients treated and followed up for over a decade at Sri Jayadeva Institute of Cardiovascular Sciences and Research (SJICR). The paper highlights the growing challenge of cardiovascular complications among HIV-positive individuals in the modern era of antiretroviral therapy. "Our findings show that even with effective HIV control and modern drug-eluting stent technology, cardiovascular risk persists," said Dr Setty.
“This underscores the importance of early risk identification, targeted secondary prevention, and integrated management strategies for this vulnerable population."
The study was a part of a decade-long registry at SJICR and investigates the interplay between HIV infection, metabolic risk factors, and coronary atherosclerosis, focusing on clinical and angiographic outcomes following PCI.
“Findings underscore the need for HIV-specific cardiovascular protocols and multidisciplinary follow-up to improve long-term survival and quality of life,” SJICR said in a statement.
Setty is an Associate Professor of Cardiology and Research Head at SJICR. In his career, he has performed over 8,000 coronary interventions. He is a Fellow of the American College of Cardiology (FACC), Society for Cardiovascular Angiography and Interventions (FSCAI), European Society of Cardiology (FESC), and American Heart Association (FAHA).