"This heinous act of terror was an obvious attack on civilians and the perpetrators of this attack and those who planned it are vicious terrorists who kill innocent people for their malicious goals," he said in a statement.
Karzai extended his heartfelt condolences and sympathies to the families of the victims.
A Presidential House spokesman said Karzai had ordered the security agencies to probe the incident.
A suicide car bomb today exploded outside the Indian embassy in Kabul, killing at least 12 people and injuring 83.
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