"The Achilles injury flared up following the second Test match in Durham and the best course of treatment is for Kevin to rest throughout the (one-day) series," Nick Pierce, the England and Wales Cricket Board (ECB) chief medical officer said in a statement on Wednesday.
Pietersen said he was disappointed to be missing out on the series which starts on Thursday.
Deccan Herald is on WhatsApp Channels| Join now for Breaking News & Editor's Picks