<p>In a new hope for couples affected by infertility, researchers have come up with a method for treating male infertility using a synthetic version of the sperm-originated protein known as PAWP.<br /><br /></p>.<p>This protein is sufficient and required to initiate the fertilisation process, showed the finding that promises to diagnose and treat cases of male factor infertility where a patient's sperm is unable to initiate or induce activation of the egg to form an early embryo.<br /><br />"PAWP is able to induce embryo development in human eggs in a fashion similar to the natural triggering of embryo development by the sperm cell during fertilisation," said Richard Oko from Queen's University in Canada.<br /><br />"Based on our findings, we envision that physicians will be able to improve their diagnosis and treatment of infertility, a problem that affects 10-15 percent of couples worldwide," Oko added.<br /><br />The results of this study highlight the potential clinical applications of sperm PAWP as a predictor of infertility treatment.<br /><br />Since most human infertility treatments are now done by injecting a single sperm directly into an egg, supplementation of human sperm with PAWP protein may potentially be used to improve the success rate of infertility treatments in the future.<br /><br />"The results of our study set the stage for further investigation of PAWP protein as a molecular marker for diagnosis and as a factor for improvement of infertility treatments," Oko added. The study was published in the FASEB Journal.</p>
<p>In a new hope for couples affected by infertility, researchers have come up with a method for treating male infertility using a synthetic version of the sperm-originated protein known as PAWP.<br /><br /></p>.<p>This protein is sufficient and required to initiate the fertilisation process, showed the finding that promises to diagnose and treat cases of male factor infertility where a patient's sperm is unable to initiate or induce activation of the egg to form an early embryo.<br /><br />"PAWP is able to induce embryo development in human eggs in a fashion similar to the natural triggering of embryo development by the sperm cell during fertilisation," said Richard Oko from Queen's University in Canada.<br /><br />"Based on our findings, we envision that physicians will be able to improve their diagnosis and treatment of infertility, a problem that affects 10-15 percent of couples worldwide," Oko added.<br /><br />The results of this study highlight the potential clinical applications of sperm PAWP as a predictor of infertility treatment.<br /><br />Since most human infertility treatments are now done by injecting a single sperm directly into an egg, supplementation of human sperm with PAWP protein may potentially be used to improve the success rate of infertility treatments in the future.<br /><br />"The results of our study set the stage for further investigation of PAWP protein as a molecular marker for diagnosis and as a factor for improvement of infertility treatments," Oko added. The study was published in the FASEB Journal.</p>