Manchester City's fear of drawing one of Europe's big guns in the Champions League round of 16 was realised on Monday when they were handed a daunting tie with four-times winners Barcelona.
Holders Bayern Munich will play Arsenal at the same stage for the second successive season while Chelsea hero Didier Drogba will make an emotional return to west London with current side Galatasaray following Monday's draw.
Nine-times winner Real Madrid take on Schalke 04 and last season's runners-up Borussia Dortmund will play Zenit St Petersburg, who scraped through with six points after winning only one of their six group games.
French champions Paris St Germain will play Bayer Leverkusen and Atletico Madrid were paired with AC Milan.
"Very tough, we are happy because we are here and we will fight for the trophy, but it's true that it could be maybe better," City director of football Txiki Begiristain, who held the same position at Barcelona and spent seven years as a player at the Spanish club, told Sky Sports.
Despite the tough draw, City will take confidence from their strong home form which has seen them score a remarkable 35 goals in eight home league matches this season, and their win over Bayern earlier this month, although it was not enough to finish top of their group.
"Barca is a champion side who are playing with confidence and they have that champion's mentality which is going to make it tough for us," Begiristain added. "But we are playing well and creating a lot of scoring chances and that gives us a lot of confidence."
Barcelona share top spot in La Liga with Atletico Madrid, and will hope to have striker Lionel Messi back from a thigh strain in time for the first leg in February. "It's a tie of exceptional quality to get the competition going again in February," Barcelona sporting director Andoni Zubizarreta told Spanish television broadcaster Canal Plus.
"They are two teams that attack very well and have a huge amount of talent right from the goalkeepers through to the forward line. It seems like it will be a match with everything and it is going to be a tough fight," he explained.
Bayern defeated Arsenal on away goals in last season's round of 16 on their way to their fifth title.
The German champions won the first game at the Emirates Stadium 3-1 but lost 2-0 at home, and their chief executive Karl-Heinz Rummenigge was not looking forward to a rematch with the Premier League leaders.
"They are the leaders in the Premier League and so we have been warned," he said.
"A few months ago we lost to them in Munich. They are a very tough team."
Chelsea have an intriguing tie against Galatasaray and former Stamford Bridge favourite Drogba.
The Ivorian ended his Chelsea career on a high after scoring the deciding penalty in the shootout success over Bayern in the 2012 final, and the London side's manager Jose Mourinho spoke recently of his hope that the two teams would meet.
Three-times winners Manchester United will play Greek champions Olympiakos Piraeus.
The final is at Lisbon's Stadium of Light on May 24.