The movie which stars Cruise as action man Ethan Hunt will not feature a number because it is not a "sequel", Contactmusic reported.
"One of the things I always wanted for the franchise was for it not to have a number afterwards. I've never done sequels to films and I never thought of these films as sequels.
Paramount has done a great job in coming up with a title, so it's not going to be MI2, 3, 4. It's going to be 'Mission: Impossible Ghost Protocol'," said the 48-year-old actor.
Dubai would witness the main film action and the world's tallest 828 metre high Burj Jalifa tower may also be involved for the breath taking action scenes.
"To be shooting here, it's a city I've always wanted to shoot in," he added.
'Mission: Impossible: Ghost Protocol' will also be shot in Prague, Vancouver and Moscow.
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