<p>The world number three took the first set 6-4 but lost the next two sets against the 16th seed on tiebreaks (7-2) (7-4) in a superb match of clean-hitting strokes. <br /><br />"I should never have lost this match," the 16-times Grand Slam champion told reporters. "He knows how close he came to losing. I had multiple chances but I couldn't make the difference. <br /><br />"I thought I was playing well but he served better towards the end and hung in there. I didn't feel I could break and it's no fun to play like that," said the Swiss, who was knocked out by Ernests Gulbis in the second round in Rome last year. <br /><br />"I'm looking forward to a few days to stay mentally and physically fresh and practice very hard. The same thing happened last year," <br /><br />World number one Rafa Nadal returned to form with a 6-4, 6-2 win over compatriot Feliciano Lopez despite almost withdrawing with a fever while fourth seed Andy Murray also progressed beating Potito Starace of Italy 6-2, 6-3.<br /><br />World number one Caroline Wozniacki targeted Grand Slam success after overpowering qualifier Anastasia Rodionova of Australia 6-2, 6-0 in the Italian Open second round on Wednesday. <br /><br />The Dane will next face Belgian Yanina Wickmayer, who came back from a set down to defeat 13th seed Ana Ivanovic 2-6, 7-6, 6-3. <br /><br />In other matches, third-seed Victoria Azarenka of Belarus crushed local Sara Errani 6-1, 6-2 to set up a clash with Russian Anastasia Pavlyuchenkova. Fourth seed Li Na skipped past Spaniard Lourdes Dominguez Lino 6-4, 6-2. <br /><br />Fifth seed Jelena Jankovic was sprightly enough in dispatching Czech Lucie Safarova 6-0, 6-3. <br /><br />Lee-Hesh exit<br /><br />Third seeds Leander Paes and Mahesh Bhupathi crashed out after being outplayed in the super tie-breaker by American pair of Sam Querrey and John Isner.<br /><br />The Indians lost 3-6, 6-3, 5-10 to their unseeded rivals in the second round in one hour and 12 minutes to make an early exit.<br /></p>
<p>The world number three took the first set 6-4 but lost the next two sets against the 16th seed on tiebreaks (7-2) (7-4) in a superb match of clean-hitting strokes. <br /><br />"I should never have lost this match," the 16-times Grand Slam champion told reporters. "He knows how close he came to losing. I had multiple chances but I couldn't make the difference. <br /><br />"I thought I was playing well but he served better towards the end and hung in there. I didn't feel I could break and it's no fun to play like that," said the Swiss, who was knocked out by Ernests Gulbis in the second round in Rome last year. <br /><br />"I'm looking forward to a few days to stay mentally and physically fresh and practice very hard. The same thing happened last year," <br /><br />World number one Rafa Nadal returned to form with a 6-4, 6-2 win over compatriot Feliciano Lopez despite almost withdrawing with a fever while fourth seed Andy Murray also progressed beating Potito Starace of Italy 6-2, 6-3.<br /><br />World number one Caroline Wozniacki targeted Grand Slam success after overpowering qualifier Anastasia Rodionova of Australia 6-2, 6-0 in the Italian Open second round on Wednesday. <br /><br />The Dane will next face Belgian Yanina Wickmayer, who came back from a set down to defeat 13th seed Ana Ivanovic 2-6, 7-6, 6-3. <br /><br />In other matches, third-seed Victoria Azarenka of Belarus crushed local Sara Errani 6-1, 6-2 to set up a clash with Russian Anastasia Pavlyuchenkova. Fourth seed Li Na skipped past Spaniard Lourdes Dominguez Lino 6-4, 6-2. <br /><br />Fifth seed Jelena Jankovic was sprightly enough in dispatching Czech Lucie Safarova 6-0, 6-3. <br /><br />Lee-Hesh exit<br /><br />Third seeds Leander Paes and Mahesh Bhupathi crashed out after being outplayed in the super tie-breaker by American pair of Sam Querrey and John Isner.<br /><br />The Indians lost 3-6, 6-3, 5-10 to their unseeded rivals in the second round in one hour and 12 minutes to make an early exit.<br /></p>