Champions are not immune to time trouble

This happened in a game at a high level where Anatoly Karpov looked clearly better against Judit Polgar but found it difficult to progress. In trying for a win he utilised all his time and ultimately found himself on the losing side.

White: Anatoly Karpov (2735) - Black: Judit Polgar (2670)                       
Budapest, 1998

Queen’s Gambit
 1.d4 Nf6 2.c4 e6 3.Nf3 c5 4.d5 d6 5.Nc3 exd5 6.cxd5 g6 7.h3 Bg7 8.e4 0–0 9.Bd3 b5
Still following Opening theory

 10.Bxb5 Nxe4 11.Nxe4 Qa5+ 12.Nfd2 Qxb5 13.Nxd6 Qa6 14.N2c4 Rd8
Interesting move!

  15.Bf4. A good reply. If  15.Qe2 Bb7 16.Nxb7 Qxb7 17.Bf4

15...Nd7 16.0–0 Nb6 17.Nxb6 Qxb6

If 17...axb6 18.Nxc8 Qxc8 19.Qb3 Qf5 20.Bc7 Rxd5 21.Qxb6 Rd2 with more less a balanced position

18.Nxc8 Raxc8 19.Rb1.

One of the most familiar position as many games have been played till this point
19...Qb7. If 19...Bd4 20.d6 c4 21.Qg4 h5 22.Qg3 Bc5 23.Rfd1 And if 19...Rd7 20.d6 Bf8 21.Qg4 Qb7 22.Rfd1 Rc6 23.Rd2 Bxd6 24.Rbd1 Qc7 25.Rd5 h5 26.Qf3 Kf8
20.d6 Bf8 21.Qd3

If 21.Qd2 Bxd6! 22.Bxd6 Rc6 23.Rfd1 Qa6 24.Qg5 Rdxd6 25.Rxd6 Rxd6 26.Qxc5 Qxa2 27.Re1 Rd8 28.b4 a6

Ended in a draw in a previous game 21...Bxd6 22.Bxd6 Rc6 23.Rfd1 Rcxd6
Black is gaining the queen for two rooks. Worth a look is 23...Qd7
24.Qxd6 Rxd6 25.Rxd6 c4

A good advance. 26.Rd2 c3 27.Rc2 Qe4 28.Rbc1 cxb2 29.Rxb2 a5 Looks like the players had done plenty of homework and followed a previous game till this move! Black now has made a new move! If 29...h5 30.g3 a5 31.Rb3 Qd5 32.Rcb1 Qd2 33.a3 Qc2 34.Rb8+ Kg7
30.Rbc2 h5. Not exactly the right choice! Stronger is 30...Qa4 31.Rd2 h5 making things difficult for white to progress

31.Rc4 Qd5 32.a4.
White looks better now!

32. ..Qd2 33.h4 Kg7 34.g3 Qb2 35.Rc5 Qd2 36.Kg2 Qb4 37.R1c4 Qb7+ 38.Kh2 Qb6 39.Kg1 Qb1+ 40.Rc1 Qb4 41.R5c4 Qd2 42.R1c3. A good move!
42. ..Qd1+ 43.Kh2 Qd2 44.Rf3 Qd5

The black queen is trying to see if one of the rooks could be made vulnerable so that it can be attacked and captured
45.Rcf4 f5. This move is more or less forced for black!  
46.Rc3 Qd2 47.Rc5 Qd8 48.Rfc4 Qd2 49.Kg2 Qd3 50.Rf4 Qd8 51.Kh2 Qd2 52.Rcc4 Qe1 [52...Kh6!?] 53.Kg2 Qe7 54.Rfd4 Qb7+ 55.Kg1 Qb1+ Black can also think about 55...Kh6 56.Rc5 Qb2
 56.Kh2 Qb2 57.Rd7+
A rather nasty check
 57...Kf6 If 57...Kh6 58.Kg2 Qb8 59.Rcc7 Qa8+ 60.Kg1 Qg8 61.Rd6
58.Rc6+ Ke5 59.Kg2 f4  60.gxf4+ Kxf4 61.Rdc7.
If 61.Rxg6 Qb4 62.Rg5 Qxa4 63.Rf7+ Ke4 64.Kg3
61...Qb3 62.Rc4+ Ke5 63.Re7+ Kd5 64.Rce4 Kd6 65.R7e5 Qd3 66.Re6+ Kd7 67.Re3 Qd5+ 68.R6e4 g5  69.hxg5 Qxg5+ 70.Kh2 Qf5 71.f3 Kd6 72.Rd3+ Kc5
White is better but difficult to make this progress
Diagram 1
73.Kg3 Qg6+ 74.Kh4 Qf5 75.Rde3 Qg6 76.Re5+ Kb4 77.R3e4+ Kc3 78.Rc5+ Kd3 79.Rf4 Qg1 80.Rd5+ Ke3 81.Rff5 Qh2+ 82.Kg5. Karpov tried and tried for a win but at this point lost out on time.
Diagram 2
White to play and win
1.Bxf6+ Kxf6 2.Be2+ Ke5 3.Bxc4 and White wins.