Itravil: Weight loss with ITRAVIL clobenzorex: The secret miracle cure

PRODUCT DETAILS About Itravil 100 Capsule

ITRACONAZOLE is a medicine that fights against fungi and yeast that cause infections on skin, mouth, nails, hands, feet, gut, throat and other parts of the body. Fungal infection is a skin problem in which a fungus harms the tissue and makes it infected. Fungal infections can be passed on from one person to another. Yeast infection is caused by a kind of fungus called candida and usually happens in wet and warm areas of the body.

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Uses of Itravil 100 Capsule Fungal infections, Yeast infections

Medicinal Benefits of Itravil 100 Capsule ITRACONAZOLE is an antifungal that treats various fungal infections on skin, mouth, nails, hands, feet, gut, throat, and other parts of the body. The fungal cells have a thin layer around them that helps them stay alive by keeping out harmful things and holding in important things. ITRACONAZOLE stops the making of ergosterol (a main part of the thin layer of fungi). This makes the thin layer weak and broken and lets the important things of fungal cells leak out. This kills the fungi and removes the fungal infection.

Directions for Use If your doctor tells you to take

ITRACONAZOLE in tablet form, swallow the whole tablet with a glass of water. If you are taking any medicine that lowers stomach acid, take ITRACONAZOLE with cola. Take ITRACONAZOLE with food to prevent stomach trouble. Do not split, crush or chew it. If it is liquid form, shake the bottle well before use and take

ITRACONAZOLE on an empty stomach at least 1 or 2 hours before meals as your doctor tells you with a measuring cup or spoon given. Injection: ITRACONAZOLE in injection form is given as a drip into a vein by a doctor or nurse. On the skin: Use ITRACONAZOLE as your doctor tells you. Wash your hands before and after using ITRACONAZOLE. Take a little amount of ITRACONAZOLE and put it as a thin layer on the clean and dry affected area.

ITRACONAZOLE is only for use on the skin. Avoid touching ITRACONAZOLE with eyes as it may make them sore. In case ITRACONAZOLE touches your eyes by mistake, wash with water well.

Side Effects of Itravil 100 Capsule

Like all medicines, ITRACONAZOLE can cause some common side effects such as feeling sick, headache, loose stools, feeling tired, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of ITRACONAZOLE are not serious and go away over time. However, if the side effects stay or get worse, please talk to your doctor."

Uses of Itravil 100 Capsule Fungal infections, Yeast infections

Things to be careful of Drug Warnings If you are allergic to ITRACONAZOLE or any other medicines, please tell your doctor. ITRACONAZOLE is not safe for pregnant women and may harm the baby in the womb. However, if you are pregnant, want to get pregnant or breastfeeding, it is better to talk to a doctor before using ITRACONAZOLE. Do not take fentanyl (a strong pain medicine that can make you addicted) with ITRACONAZOLE, as it may make it hard for you to breathe and can even kill you. Do not take ITRACONAZOLE if you had a problem with your heart as it may cause very serious bad effects. If you see a yellow colour change of your eyes or skin, dark coloured pee, stomach pain, light coloured poo, no hunger, unusual tiredness, throwing up or feeling sick, stop taking ITRACONAZOLE and talk to a doctor right away as they might be signs of liver failure. If you have problems with your kidney, liver, heart or lung, tell your doctor before taking ITRACONAZOLE.

Drug Interactions

Drug-Drug Interaction:

ITRACONAZOLE may not work well with antacids (esomeprazole, omeprazole, pantoprazole), medicines that reduce swelling (fluticasone, budesonide), pain medicines that can make you addicted (hydrocodone), medicines that prevent blood clots (warfarin), medicines that lower blood cholesterol (simvastatin), medicine that stops allergies (terfenadine) and medicine that calms you down (alprazolam).

Drug-Disease Interaction:

Do not take ITRACONAZOLE if you had a problem with your heart as it may cause very serious bad effects. If you have problems with your kidney, liver, heart or lung, tell your doctor before taking ITRACONAZOLE."

It contains Clobenzorex Itravil Ap has clobenzorex hydrochloride in it. This is a type of clobenzorex. You can find Itravil Ap in these countries:

Mexico Important Notice: The Drugs.com international database is not finished yet. It may have some mistakes. It is not a replacement for the advice and judgment of your doctor, pharmacist or other healthcare professional. It does not mean that any medicine in any country is safe, right or good for you. Talk to your healthcare professional before taking any medicine.Disclaimer We have tried to make sure that the information we give is correct, up-to-date and complete, but we cannot promise that.

Also, the drug information we give may change over time and you should not use it as a source of information after this date. This material does not support drugs, test patients, or suggest therapy. This information is a help resource that you can use with, and not instead of, the expertise, skill, knowledge, and judgment of healthcare practitioners in patient care. Just because we do not warn you about a drug or a combination of drugs, it does not mean that they are safe, effective, or good for any patient.

Drugs.com is not responsible for any part of healthcare that you get with the help of the materials we give. The information we give does not cover all the possible ways to use, follow, avoid, warn, interact, react, or affect drugs. If you have questions about the things you are taking, ask your doctor, nurse, or pharmacist.

Numbers in medical articles show general patterns, not personal advice. Different things can change a lot for different people, so always look for personal medical help for your specific healthcare choices."

Product Details

 We are a well-known name in this area, engaged in offering high-quality ITRAVIL 30MG CAPSULES.

1.  We are praised as one of the most flexible businesses in this field, involved in offering great-quality ITRAVIL 30 MG CAPSULES.

2.  USES:An indication is a word used for the list of problems or signs or sickness for which the medicine is given or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor gives it for a headache or body aches. Now fever, headache and body aches are the indications of paracetamol. A patient should know the indications of medications used for common problems because they can be bought over the counter in the pharmacy without prescription by the Doctor."

Clobenzorex (Asenlix) is a medicine that reduces appetite and is changed by the body into amphetamine, a drug that can make people feel alert and energetic. This makes it hard to tell if someone has used amphetamine or clobenzorex when they take a drug test. Previous research has shown that clobenzorex and some of its breakdown products are passed out in urine. Clobenzorex can be found in urine for up to 29 hours after taking it, using a very sensitive test.

However, some urine samples that had high levels of amphetamine (> or = 500 ng/mL) did not have any clobenzorex in them. This means that someone could have used clobenzorex even if it is not in their urine. To check more accurately if someone has used clobenzorex, another breakdown product was looked at. One study found that some unknown substances with an oxygen atom attached to

clobenzorex were present in urine for as long as amphetamine was in some people. To see if one of these substances with oxygen could be used to confirm clobenzorex use in urine samples that had amphetamine, 4-hydroxy clobenzorex was made for this study. This substance was easy to find and was usually higher than amphetamine in urine samples that had amphetamine, even after clobenzorex was gone. Urine samples from a study where people took one dose of clobenzorex (30 mg) were tested for the presence of the substance with oxygen. The testing method used acid to break down the substance, then separated it from the urine and measured it with a machine that uses gas and a magnet.

The machine looked for particles with specific weights of 125, 330, and 364. 4-Hydroxy Clobenzorex and another similar substance with chlorine were used to identify and measure the substance with oxygen. The highest levels of the substance with oxygen were found around 1:30-5:00 hours after taking clobenzorex and ranged from about 5705 to 88,410 ng/mL. Most importantly, however, all urine samples that had amphetamine at > or = 500 ng/mL also had some of the substance with oxygen in them (LOD 10 ng/mL), making it a useful way to tell apart clobenzorex use from illegal amphetamine use.``

THERAPEUTIC INDICATIONS THERAPEUTIC INDICATIONS:

Appetite suppressant indicated as an aid in the treatment of obesity caused by external factors, associated with a low-calorie diet and exercise, with a Body Mass Index (BMI) ≥30 kg/m2 or overweight with BMI ≥ 27 kg/m2 with some related health problem (e.g. High blood pressure, high cholesterol, type 2 diabetes, sleep apnea, osteoarthritis).

Several clinical studies have shown that the drug treatment along with lifestyle changes is better than just lifestyle changes to achieve a significant weight loss (>5%) in patients with overweight and obesity.PHARMACEUTICAL PROPERTIES

PHARMACOKINETICS AND PHARMACODYNAMICS:

PHARMACOKINETICS: Clobenzorex is well absorbed in the gastrointestinal tract, reaching its maximum concentration in 60 to 120 minutes and the plasma levels vary from 8 to 47 ng/ml. Clobenzorex binds to plasma proteins in approximately 15% - 30%, it distributes widely in the tissues. Its half-life is very variable, from 1 to 17 hours. It is metabolized to 4-hydroxy clobenzorex that is eliminated by the kidney.

PHARMACODYNAMICS: ITRAVIL IFA® is a sympathomimetic amine that acts on the ventrolateral nucleus of the hypothalamus, increasing the release of noradrenaline and dopamine in the synaptic spaces and decreasing their uptake in the presynaptic nerve endings, so the net effect is an increase of the concentrations of adrenaline and dopamine. Noradrenaline acts mainly to stop the appetite, activating the alpha 4 and beta 1 receptors in the hypothalamic nuclei.

Clobenzorex also acts at the central level, increasing the thermogenic activity in the brown fat tissue, so it should also be considered as a drug that increases the energy expenditure.CONTRAINDICATIONS

CONTRAINDICATIONS:

– Pulmonary arterial hypertension.

– Severe arterial hypertension.

– History of cardiovascular or cerebrovascular disease.

– Psychiatric disorders including anorexia and depression.

– Tendency to consume drugs, known alcoholism.

– Children under 12 years old and elderly.

– Advanced stages of atherosclerosis.

– Hyperthyroidism.

– Hypersensitivity or known idiosyncrasy to the sympathomimetic amines.

– Closed-angle glaucoma.

– Risk of urinary retention linked to urethra prostatic disorders.

– States of agitation.

– Concomitant use of antidepressants or monoamine oxidase inhibitors (MAOI). ITRAVIL IFA® should not be administered for 14 days after taking MAOI as hypertensive crises could occur.ADVERSE REACTIONS SECONDARY AND ADVERSE REACTIONS: No systematic reports of adverse events with Clobenzorex have been identified and the frequency of adverse reactions is not defined.

Epidemiological studies have shown that the intake of appetite suppressants is a risk factor involved in the development of arterial hypertension, pulmonary and that its use is strongly associated with an increased risk of such adverse reaction. In patients treated with Clobenzorex, cases of pulmonary arterial hypertension have been described, a severe and often fatal disease. The first clinical sign is usually the presentation of exercise dyspnea, which requires the suspension of treatment and the study of the patient in a specialized service.

Since Clobenzorex is a sympathomimetic amine, side effects consistent with this class of drugs can be expected, the most common adverse reactions are:

Central Nervous System

Psychopathic or psychotic reactions, depression, nervousness, agitation, sleep disorders, dizziness, seizures and headache.

Cardiovascular

Tachycardia, palpitations, hypertension and chest pain.

Contraindications Clobenzorex Allergy to the ingredients of the formula; elderly or children under 12-16 years old; patients with pulmonary hypertension or severe high blood pressure; history of heart or brain disease; psychiatric disorders, including nervous anorexia and depression; history or tendency to use drugs and alcohol; advanced hardening of the arteries; overactive thyroid; allergy or known intolerance to the sympathomimetic amines; enlarged prostate or any blockage of the urinary tract; closed-angle glaucoma; states of restlessness; do not use together with other appetite suppressants that act on the brain, because of the increased risk of developing pulmonary hypertension with potentially deadly consequences, or with antidepressants or MAOI, it should not be administered for 15 days after taking an MAOI because of the risk of having hypertensive crises.

Warnings and precautions Clobenzorex Strict medical control; before prescribing clobenzorex, organic causes of obesity must be ruled out; include dietary and psychotherapeutic measures; risk of severe pulmonary high blood pressure, so the therapeutic indications and duration of treatment must be respected, a treatment longer than 3 months and a BMI =30 kg/m2 increases the risk of pulmonary high blood pressure, appearance or worsening of shortness of breath during exercise suggests the possibility of pulmonary high blood pressure, so the treatment must be stopped immediately and the patient go to a specialized center; heart and brain accidents, often after a rapid weight loss. In obese patients with risk of vascular disease, special care must be taken to ensure a gradual and controlled weight loss; patients with history of brain or heart disease; the sympathomimetic amines lose the appetite suppressant power after several weeks of treatment; long-term treatment can cause dependence with withdrawal syndrome when stopping the treatment and severe psychotic disorders in patients with predisposition; epileptic patients; do not stop the treatment abruptly, unless it is because of some adverse reaction.

Interactions Clobenzorex Take 15 days after stopping a treatment with an MAOI, as hypertensive crises could occur; tricyclic antidepressants and serotonin reuptake inhibitors such as venlafaxine and citalopram as they increase the risk of having serotonin syndrome; guanethidine or its derivatives as they share the same place of action and guanethidine and its derivatives could be displaced reducing their anti-high blood pressure effect; phenylethylamine derivatives, appetite suppressants such as sibutramine and tricyclic antidepressants, as they can enhance the effects on blood pressure of the latter; sympathomimetic agents and anesthetics in general can cause irregular heartbeats. Lab: positive reaction in the doping tests

Pregnancy Clobenzorex Given the insufficient clinical experience, its use is not recommended

Breastfeeding Clobenzorex Given the insufficient clinical experience, its use is not recommended

Adverse reactions Clobenzorex Pulmonary high blood pressure; pharmacological tolerance, dependence and withdrawal syndrome; psychotic or psychosis reactions, depression, nervousness, agitation, sleep disorders and dizziness; tachycardia, palpitations, high blood pressure and chest pain; dry mouth and constipation; painful or difficult urination and urinary retention

© Vidal Vademecum Source: The content of this monograph of active ingredient according to the ATC classification, has been written taking into account the clinical information of all the medicines authorized and marketed in Mexico classified in that ATC code. To know in detail the information authorized by COFEPRIS for each medicine, you should consult the corresponding Technical Sheet authorized.

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Itravil AP 60 mg. Clobenzorex 60 mg.

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Common questions about Itraconazole

Q. What is Itraconazole used for?

Itraconazole is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of feet, or infection in groin and buttocks. This medicine also treats lasting infection of fingernails and toenails, lasting candida (yeast) infections of candida (yeast) infections of the mouth or throat in patients with lower immunity to disease. It is also used in the treatment of cryptococcal infection and infections caused by histoplasma, aspergillus and blastomyces.

Q. For how long do I need to take Itraconazole?

The dose and time of treatment will depend on the kind and place of infection and your reaction to the treatment. For example, if you are taking Itraconazole for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days. While, on the other hand, if you are taking it for candidal infection of the dose may take about 1 to 3 3 days depending on the amount suggested by the doctor.

Q. What should I do if I miss a dose of Itraconazole?

If you forget to take your dose, take the missed dose as soon as you remember. However, if it is time for your next dose, skip the missed dose and continue with your regular plan. Do not take two doses to make up for the missed dose.

Q. I am taking Itraconazole for nail infection but there does not seem to be any improvement. Can I stop taking it?

No, you should not stop taking Itraconazole without finishing the whole course. This is because if you stop the medicine then your fungal infection may not get fully cured. It usually takes about 6-9 months for the nail wounds to get cured and after that the new nail also takes several months to grow. Therefore, do not worry if you do not see any improvement during the treatment.

Q. Why has my doctor asked me to get blood tests done?

Your doctor may have asked for blood tests to check your liver’s working. This is because the use of Itraconazole may cause serious liver damage. Therefore, if you have loss of appetite, nausea, vomiting, dark urine or stomach pain while taking Itraconazole, quickly tell your doctor.

Q. Can I take an antacid and Itraconazole together?

Itraconazole can be used by the body if there is enough acid in the stomach. Medicines for stomach ulcers, heartburn or indigestion make the acid produced by the stomach less strong. Therefore, it is suggested to avoid taking antacids or any such medicine for at least 2 hours after taking Itraconazole. However, if you are taking antacids (medicines that prevent the production of stomach acid), take Itraconazole capsules with a drink of cola.

Q. What is drug resistance?

Is it possible to develop resistance to Itraconazole? Drug resistance is a situation when the fungi change in your body and the medicine is not able to work. There are reports which show resistance of some candida species (krusei, glabrata and tropicalis) with Itraconazole. Itraconazole should not be used for infection caused by these species. It is suggested to take the whole course of Itraconazole to avoid drug resistance.

Q. I am on alprazolam for quite some time. Is it okay if I start Itraconazole now?

Yes, you can take both Alprazolam and Itraconazole together, but keep an eye on the side effects of Alprazolam such as feeling dizzy or sleepy. If you have side effects after taking Itraconazole, talk to your doctor who will change the dose of alprazolam.

Q. My doctor gave Itraconazole to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?

Your doctor did not give Itraconazole to your friend because Itraconazole affects the working of dofetilide. This effect can cause trouble in the electrical activity of the heart, which can be bad for the patient.