Bernardo Silva and Goncalo Guedes return to Portugal's starting line-up for Saturday's World Cup last-16 tie against Uruguay in Sochi.

The pair come in along with right-back Ricardo Pereira as coach Fernando Santos makes three changes to the European champions' starting XI from their 1-1 draw with Iran in their final group game.

Cedric Soares and Andre Silva drop out along with Ricardo Quaresma, who netted Portugal's goal in that match.

Guedes should start up front alongside skipper Cristiano Ronaldo, who scored a hat-trick on his last appearance at the Fisht Stadium in the 3-3 draw with Spain in the group stage.

Jose Gimenez returns in central defence for Uruguay after missing their last group outing, a 3-0 win over hosts Russia.

The prolific pairing of Luis Suarez and Edinson Cavani lead the South American side's attack, with the winners of this tie going through to a quarter-final against France.

The French beat Lionel Messi's Argentina 4-3 in a thriller in Kazan earlier on Saturday.

Starting line-ups for the World Cup last-16 tie between Uruguay and Portugal in Sochi on Saturday (1800 GMT kick-off):

Uruguay (4-4-2)

Fernando Muslera; Martin Caceres, Jose Gimenez, Diego Godin (capt), Diego Laxalt; Nahitan Nandez, Lucas Torreira, Matias Vecino, Rodrigo Bentancur; Luis Suarez, Edinson Cavani

Coach: Oscar Tabarez (URU)

Portugal (4-4-2)

Rui Patricio; Ricardo Pereira, Pepe, Jose Fonte, Raphael Guerreiro; William Carvalho, Adrien Silva, Joao Mario, Bernardo Silva; Goncalo Guedes, Cristiano Ronaldo (capt)

Coach: Fernando Santos (POR)

Referee: Cesar Ramos (MEX)