<p> Defending champion Petra Kvitova crashed out of the Madrid Open when she was upset by Czech compatriot Lucie Hradecka 6-4, 6-3 in the second round on Wednesday. <br /><br /></p>.<p>The world number four and seeded third this year, Kvitova used her 2011 success at the premier clay event in the Spanish capital as a springboard for a first Grand Slam singles title at Wimbledon and went on to triumph at the season-ending WTA championships. <br /><br />The graceful left hander has yet to win a title this year, however, after claiming six last season, and had her serve broken five times by Hradecka, ranked 105th in the world. <br /><br />There were no such problems for Agnieszka Radwanska of Poland, who leap-frogged Kvitova to number three in the latest rankings, in her second-round match against Sara Errani. Radwanska snapped Errani’s 16-match winning streak on clay, which netted her titles in Acapulco, Barcelona and Budapest, with a dominant performance, crushing the Italian 6-0, 6-1 to set up a third-round meeting with another Italian, Roberta Vinci. <br /><br />Meanwhile, American eighth seed John Isner was pipped 7-6, 7-6 in the second round by fellow big-serving giant Marin Cilic. <br /><br />Unseeded Croat Cilic produced when it counted in the tiebreaks on the blue clay at the Magic Box arena, winning the first 7-4 and the second 7-3 to set up a meeting with former US Open champion Juan Martin Del Potro or Mikhail Youzhny. <br /><br />Neither player managed to break the other's serve as Cilic followed up his five-set victory over Isner at last year’s Australian Open, their only previous meeting, with another narrow success. <br /><br />Isner refused to blame the reverse on the blue clay, a controversial innovation at this year's edition of the Masters event that has prompted harsh criticism from a list of players. <br /><br />Spaniard Rafael Nadal, who is chasing a third straight clay title of the season, gets his campaign under way later on Wednesday with a second-round clash against former world number three Nikolay Davydenko of Russia. <br /><br />Current number three Roger Federer then plays fast-rising Canadian Milos Raonic, who took a set off the Swiss maestro at the Indian Wells Masters in March. Djokovic will meet unseeded Stanislas Wawrinka, in the third round on Thursday.<br /></p>
<p> Defending champion Petra Kvitova crashed out of the Madrid Open when she was upset by Czech compatriot Lucie Hradecka 6-4, 6-3 in the second round on Wednesday. <br /><br /></p>.<p>The world number four and seeded third this year, Kvitova used her 2011 success at the premier clay event in the Spanish capital as a springboard for a first Grand Slam singles title at Wimbledon and went on to triumph at the season-ending WTA championships. <br /><br />The graceful left hander has yet to win a title this year, however, after claiming six last season, and had her serve broken five times by Hradecka, ranked 105th in the world. <br /><br />There were no such problems for Agnieszka Radwanska of Poland, who leap-frogged Kvitova to number three in the latest rankings, in her second-round match against Sara Errani. Radwanska snapped Errani’s 16-match winning streak on clay, which netted her titles in Acapulco, Barcelona and Budapest, with a dominant performance, crushing the Italian 6-0, 6-1 to set up a third-round meeting with another Italian, Roberta Vinci. <br /><br />Meanwhile, American eighth seed John Isner was pipped 7-6, 7-6 in the second round by fellow big-serving giant Marin Cilic. <br /><br />Unseeded Croat Cilic produced when it counted in the tiebreaks on the blue clay at the Magic Box arena, winning the first 7-4 and the second 7-3 to set up a meeting with former US Open champion Juan Martin Del Potro or Mikhail Youzhny. <br /><br />Neither player managed to break the other's serve as Cilic followed up his five-set victory over Isner at last year’s Australian Open, their only previous meeting, with another narrow success. <br /><br />Isner refused to blame the reverse on the blue clay, a controversial innovation at this year's edition of the Masters event that has prompted harsh criticism from a list of players. <br /><br />Spaniard Rafael Nadal, who is chasing a third straight clay title of the season, gets his campaign under way later on Wednesday with a second-round clash against former world number three Nikolay Davydenko of Russia. <br /><br />Current number three Roger Federer then plays fast-rising Canadian Milos Raonic, who took a set off the Swiss maestro at the Indian Wells Masters in March. Djokovic will meet unseeded Stanislas Wawrinka, in the third round on Thursday.<br /></p>