<p>Roger Federer will need to avoid a second Grand Slam upset at the hands of home favourite John Millman if he wants to bring up 100 wins at the Australian Open on Friday.</p>.<p>The 38-year-old Swiss, already the first man to win 100 matches at Wimbledon, can match the feat in Melbourne if he beats Millman, ranked 47, in the third round.</p>.<p>But the 20-time Grand Slam champion is well aware of the challenge posed by Millman, after he was shocked by the Australian in four punishing sets at the 2018 US Open.</p>.<p>"I think the next match is really going to be a test for me because John is going to be there. He's fit like a fiddle," Federer said.</p>.<p>"He's from this country, so naturally also it's going to be different intensity. I think this is going to be a good test for me."</p>.<p>Friday's glamour tie is between 15-year-old American Coco Gauff and defending champion Naomi Osaka, 22, the second instalment of a rivalry that could run and run.</p>.<p>Osaka destroyed Gauff at the same stage of the US Open last year but the assertive teenager insisted it will be different this time around.</p>.<p>"She plays really aggressive. This time coming in I'm going to be more aggressive," said Gauff.</p>.<p>"I think I'm more confident this time around."</p>.<p>Serena Williams, seeking to end her quest for a record-equalling 24th major title, plays China's Wang Qiang, while Australia's world number one Ashleigh Barty faces Elena Rybakina.</p>.<p>Reigning men's champion Novak Djokovic, who dismissed Tatsuma Ito in round two, will face a second Japanese opponent when he plays Yoshihito Nishioka.</p>.<p>Defeat is almost unthinkable for the seven-time Melbourne winner, who dropped only three games to Nishioka in their only previous meeting at last year's Davis Cup.</p>.<p>Sixth seed Stefanos Tsitsipas will face a sterner test against Canada's Milos Raonic, a quarter-finalist last year, while Italy's Fabio Fognini, who has already survived two five-setters, plays Guido Pella.</p>
<p>Roger Federer will need to avoid a second Grand Slam upset at the hands of home favourite John Millman if he wants to bring up 100 wins at the Australian Open on Friday.</p>.<p>The 38-year-old Swiss, already the first man to win 100 matches at Wimbledon, can match the feat in Melbourne if he beats Millman, ranked 47, in the third round.</p>.<p>But the 20-time Grand Slam champion is well aware of the challenge posed by Millman, after he was shocked by the Australian in four punishing sets at the 2018 US Open.</p>.<p>"I think the next match is really going to be a test for me because John is going to be there. He's fit like a fiddle," Federer said.</p>.<p>"He's from this country, so naturally also it's going to be different intensity. I think this is going to be a good test for me."</p>.<p>Friday's glamour tie is between 15-year-old American Coco Gauff and defending champion Naomi Osaka, 22, the second instalment of a rivalry that could run and run.</p>.<p>Osaka destroyed Gauff at the same stage of the US Open last year but the assertive teenager insisted it will be different this time around.</p>.<p>"She plays really aggressive. This time coming in I'm going to be more aggressive," said Gauff.</p>.<p>"I think I'm more confident this time around."</p>.<p>Serena Williams, seeking to end her quest for a record-equalling 24th major title, plays China's Wang Qiang, while Australia's world number one Ashleigh Barty faces Elena Rybakina.</p>.<p>Reigning men's champion Novak Djokovic, who dismissed Tatsuma Ito in round two, will face a second Japanese opponent when he plays Yoshihito Nishioka.</p>.<p>Defeat is almost unthinkable for the seven-time Melbourne winner, who dropped only three games to Nishioka in their only previous meeting at last year's Davis Cup.</p>.<p>Sixth seed Stefanos Tsitsipas will face a sterner test against Canada's Milos Raonic, a quarter-finalist last year, while Italy's Fabio Fognini, who has already survived two five-setters, plays Guido Pella.</p>